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The Perioperative Application of Low Molecular Weight Heparin in Preventing Deep Vein Thrombosis for Elderly Patients with Hip Fracture

Author: WangQiang
Tutor: ShengWeiBin
School: Xinjiang Medical University
Course: Orthopaedic Surgery
Keywords: Of deep venous thrombosis Hip fractures Low molecular weight heparin Perioperative prevention
CLC: R654
Type: Master's thesis
Year: 2008
Downloads: 173
Quote: 0
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Abstract


Objective: To investigate the low molecular weight heparin to prevent hip fractures efficacy and safety of deep venous thrombosis (DVT) occurred in the perioperative period. Methods: age greater than 60 years old around the hip fracture patients 70 patients were randomly divided into two groups, the control group, 38 cases, 32 cases of the experimental group. The control group underwent physical methods of prevention (the ankle passive or active movement, massage the lower extremity, lower extremity muscle isometric contraction); experimental group physical methods to prevent the low-molecular-weight heparin prophylaxis. , Respectively, at the time of admission, preoperative, postoperative 1 day, 10 days after surgery to check blood coagulation; admission, preoperative and postoperative 10 days, after 1 month, 3 lower extremity venous color Doppler ultrasound examination to understand Are there The venous thrombosis record blood loss, postoperative drainage between the two groups were compared. Results: In the control group, 38 cases of preoperative seven cases of DVT formation, the rate was 18.42%, the test group of 32 patients in the preoperative one cases of DVT incidence of 0%, the difference was statistically significant (P lt; 0.05); The control group of 31 cases, 8 cases after DVT, the incidence of 25.81%, the experimental group of 32 patients, 2 patients DVT, the incidence of 6.25%; difference was statistically significant (P lt; 0.05). The admission of the control group and the experimental group, the preoperative and postoperative platelet count showed no statistical difference (P gt; 0.05), and platelet count between the control group and the experimental group were statistically no difference in sex (P gt; 0.05); the control group, the experimental group admission PT, APTT preoperative the PT, APTT comparative statistical differences in sex (P gt; 0.05), and the control group and the experimental group and there is no statistical difference (P gt; 0.05 compare statistically); admission control group, the experimental group, the hemoglobin content preoperative hemoglobin content showed no significant differences (P gt; 0.05) decline with admission, postoperative hemoglobin content of the control group, the experimental group, two groups of preoperative hemoglobin differences (P lt; 0.01), postoperative hemoglobin content of the experimental group compared with the control group, postoperative hemoglobin content statistically no difference (P gt; 0.05). Select a large number of cases of femoral head arthroplasty in patients with blood loss, postoperative drainage comparison, 20 cases of the experimental group, the average amount of bleeding, postoperative drainage with the control group of 19 patients a slight increase statistically were no differences in sex (P gt; 0.05), and no cases of bleeding complications. Conclusion: The application of low-molecular-weight heparin effective prevention of hip fracture patients Wai operative DVT occurred; platelets, hemoglobin, no effect on the clotting mechanism; no significant increase in blood loss, postoperative drainage, does not affect the conduct of the operation.

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