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Objective: 1. Explore the impact of nutrition support therapy on immune function in patients with leukemia remission. 2 nursing intervention on the immune function of patients with leukemia: experimental: to explore nutritional support for the treatment of immune function in patients with leukemia in remission. Department of Hematology, Second Hospital of Shanxi Medical leukemia remission in patients with a total of 60 cases, including 32 males and 28 females, aged 8-58 years old, with an average age of 35. Patients were achieved remission after chemotherapy period associated with protein - energy malnutrition. 60 leukemia patients in remission, were randomly divided into a control group and high nutritional recipes group of high-energy, and give appropriate diet in January, evaluation and nutritional status of patients, the ELESA method determination of serum cytokines IL-4, γ-IFN content, flow cytometry technology was measured in peripheral blood lymphocyte immune cells in T helper cell Th1/Th2, cytotoxic T cells CTLs, the proportion of regulatory T cells Treg. Results: complete remission of the leukemia patients after nutrition support therapy in January, the high nutritional high energy recipes patients protein - energy malnutrition was corrected, blood lipid, serum protein levels tended to increase. Serum cytokines IL-4, γ-IFN were higher (P lt; 0.01). Reducing the proportion of regulatory T cells in the peripheral blood (P lt; 0.01), cell number decreased secretion of IL-10 immunosuppressive molecules; increased Th cell, and induction of Th0 cells to Th1 cells transformed (P lt; 0.01); CTL cells increase the secretion of perforin cells increased significantly (P lt; 0.01). Summary: leukemia patients in remission often accompanied by protein - energy malnutrition, nutritional support and treatment can correct the patient's nutritional status, can improve the body's immune function, reduce immune suppression, increased anti-tumor effect. Experiment 2 investigated the impact of nursing intervention on the immune function of patients with leukemia. 60 leukemia patients and associated with protein - energy malnutrition, were randomly divided into a control group and nursing intervention group, care methods in addition to the basic clinical care also includes modern psychology, diet, family care, control group using a simple clinical care. Nursing intervention were taken after January peripheral blood of patients with the separation of serum and a single nuclear cell immune function evaluation, application ELESA Determination of serum cytokines IL-4, γ-IFN content of immune cells by flow cytometry technology Th1/Th2, CTL, Trg Determination. The results: patients with leukemia in January after nursing intervention, the patient's immune low to be corrected, blood lipids, serum protein levels tended to increase. Serum cytokines IL-4, γ-IFN were higher (P lt; 0.01). Treg cells in the peripheral blood of reducing the proportion (P lt; 0.01), cell number decreased secretion of IL-10 immunosuppressive molecules; Th cell increases, and the induction of Th0 cells to Th1 cells transformed (P LT; 0.01); increased CTL cells, CTL cells and the secretion of perforin activity increased significantly (P lt; 0.01). Summary: leukemia patients associated with protein - energy malnutrition, through modern methods of care, can improve the patient's immune function, increasing the patient's anti-tumor effect conclusions: nutrition support therapy can correct the nutritional status of patients with leukemia in remission, can improve the body's immune function, reduced immune suppression function to increase the anti-tumor effect; modern nursing intervention can improve the patient's immune function, and increase the anti-tumor effects in patients
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