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Preparation Method Study of Acetyl Cellulose Aqueous Dispersion

Author: YangDaWei
Tutor: HeXin
School: Heilongjiang University of Traditional Chinese Medicine
Course: Pharmaceutical preparations
Keywords: Cellulose acetate Aqueous dispersion Emulsion phase inversion Demulsification Organic residues Particle size and particle size distribution
CLC: R944
Type: Master's thesis
Year: 2010
Downloads: 131
Quote: 1
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Abstract


Penetration of organic solvents on the environment caused by pollution in the preparation process of the pump tablets as well as toxicity to the operator to resolve a series of problems , this paper transformed into a controlled-release tablets coating material cellulose acetate aqueous dispersion preparation conduct a more in - depth studies . Using innovative methods - emulsion the transfer phase ethanol demulsification - centrifugal dispersion method to prepare a cellulose acetate aqueous dispersion , by the type and amount of emulsifier , the dilution of the emulsion in the organic phase the solvent ratio and the water dispersion preparing process and demulsification Filter , cellulose acetate aqueous dispersion settling velocity and particle size and distribution , as evaluation indexes, and filter out the optimal formulation and process of the aqueous dispersion of cellulose acetate was prepared . Compatibility of the water dispersion of the cellulose acetate prescription , particle size distribution , stability, etc. were investigated. The experimental results show that the cellulose acetate prepared in accordance with the optimal prescription water dispersion average particle diameter of 1.40μm, and better stability . Triethyl citrate as plasticizer , the use of membrane casting SYSTEM free aqueous dispersion of cellulose acetate membranes were prepared , and the aqueous dispersion of cellulose acetate to free the glass transition temperature of the film , and mechanical properties, moisture-permeable and soluble substances were determined the elution rate .

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CLC: > Medicine, health > Pharmacy > Pharmacy > Formulations
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