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For clinical treatment of acute and chronic rhinitis and sinusitis Biyuan soft capsule prescription effective experience side has been in the clinical application of a tablet . Pharmaceutical standards Chinese medicine Narikata preparations for the Ministry of Health Biyuan piece , primarily for the treatment of acute and chronic rhinitis and sinusitis , attending the function for the heat poison nasal passage for chronic rhinitis and paranasal sinuses efficacy . Because of its taking large , disintegrating slow , clinical application has been limited . For the convenience of patients , improve the quality and efficacy of this article under the guidance of the theory of traditional Chinese medicine , the use of modern pharmaceutical technology to its formulation of reform study . In this study, as a raw material , herbal Xanthium , magnolia , honeysuckle , madder , wild chrysanthemum after with accessories made of suspension like soft capsule contents extracted pressed into soft gelatin capsules . Orthogonal experimental method in the study were screened , respectively, of a single flavor of herbs extraction process , the preferred extraction process by the three batches in pilot production enlarge , the results show that the preferred Biyuan soft capsule preparation process reproducibility , the production product quality is stable and controllable , easy - to - large-scale production . And the soft capsule preparation of Biyuan raw materials and finished products using thin layer chromatography and high performance liquid chromatography to develop research quality standards , quality standards established by the three batches of pilot sample test validation and Beijing Institute for Drug Control the quality standard of review , the results showed that the developed Biyuan soft capsule quality standards with good reproducibility , specificity to achieve good control of product quality purposes . Useful attempt in the modernization of traditional Chinese medicine , the purpose it is necessary to change its traditional formulation , but also its main ingredients quantitative analysis , in order to control its quality , in order to adapt to the standardization of traditional Chinese medicine quality control , standardized so that it reached effective, safe , controllable , and to provide a basis for the traditional Chinese medicine to the world .
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