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The Heterocyclic Compounds widespread in nature , to attract the attention of many scientists because of its wide range of biological activity . Wherein the triazolinone ketone derivatives are an important class of nitrogen - containing heterocyclic compound . Three Wow morpholine ketone derivatives have a wide range of biological activity , especially in the herbicide , with its high efficiency , low toxicity , environmentally friendly characteristics become one of the most popular topics in the field of contemporary herbicide research , especially in the past 20 years , triazolinone pesticides cause major pesticide attention . In this paper, the basis for the work of our group pre- route optimization and do further study of the herbicidal activity of activity performed better in the previous work compounds Y5060 ; same time , in order to seek the high activity of the compounds , compound Y5060 for the pilot , according to the activity the sub- structural stitching, biological row replaced its structural transformation , and synthesis of a series of new compounds , and the study of the biological activity . Specific studies are as follows : 1 . Article summarizes the progress of the ketone derivatives Triazolinone pesticide, medicine , and other fields of study . Provides a theoretical basis for the design of the synthesis of novel triazole - one derivatives . 2 summarizes the preliminary studies , route optimization outstanding herbicidal activity of the compounds Y5060 , and do in-depth study of the weeding . Compound Y5060 for the pilot , according to the method of the the active subunit structure stitching , biological and other row replaced its structural transformation , and synthesis of a series of novel triazole - ketones , all the compounds use ~~ 1H NMR , MS , elemental analysis characterized. 4 Synthesis of Compound herbicidal activity tests . 150 gai / ha concentration measured compounds on barnyardgrass, crabgrass , bluegrass, mustard , Amaranthus retroflexus , of Eclipta prostrata six weed potted activity , compounds Ik, Il , I m Eclipta prostrata inhibitory activity 70%: compound I p, I q of barnyard grass , Poa inhibitory activity of 60% inhibitory activity was 50% crabgrass .
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