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Objective To investigate the early diagnosis and treatment of fat embolism syndrome . Methods Retrospective analysis of 12 cases of fat embolism syndrome in patients with major clinical features , statistics for each patient early clinical manifestations , and calculate the distance of the first symptom of injury time , analysis of statistical hypoxemia , difficulty breathing , unconsciousness , high fever ( body temperature greater than 39 ° C ) , skin and mucous membrane bleeding , the X piece was blizzard changes in these clinical observations positive indicators of the number of cases , to find more reliable early diagnostic indicator ; analysis of 12 patients, rescue treatment experiences and lessons , summarized points of fat embolism syndrome . Early results in 12 patients showed varying degrees of hypoxemia the distance injury time of 15 hours ; 6 patients early manifestations of difficulty in breathing , the average distance injury time of 17 hours ; 5 patients early altered mental status , start showed abnormal excitement , irritability , late manifestations of conscious indifference , light coma , coma ; 2 patients early manifestations of unexplained high fever , body temperature greater than 39 ° C , the skin and mucous membrane bleeding seen in two cases , the bleeding site in the neck and shoulder supraclavicular area ; X - ray lung was the blizzard change seen in 4 patients . Common elements of treatment, all patients are taken to correct hypoxemia and use of hormone -based, integrated treatment , a total of 9 cases were cured , 2 patients died , one cases of vegetative state . Conclusion hypoxemia FES main clinical manifestations of early treatment of FeS -based, integrated treatment of respiratory support and application of large doses of hormones .
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