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The PRRS Attenuated Vaccine Immunity Effect Appraises and Oderman-1 to Its Immunity Effect Influence

Author: LiYao
Tutor: WenLiXin
School: Hunan Agricultural University
Course: Veterinary
Keywords: Blue ear disease Blue ear disease attenuated vaccine Piglets Immunological stress Immunization failure Immune-enhancing modifier
CLC: S858.28
Type: Master's thesis
Year: 2010
Downloads: 36
Quote: 0
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Abstract


[Objective] in modern pig production, often immune failure and immunosuppressive brought serious losses to swine production. Especially for farms presented immunosuppressive blue ear pig disease, has been the people's concern for its immune effect. Select three companies PRRS attenuated vaccine immunization test, evaluation of PRRS attenuated vaccine only to explore the reasons for the failure of the pig immune immune effects as well as explore the Oder market PRRS vaccine Man No. 1 (blue ear disease vaccine enhanced modifier Patent Application No.: 2008101439167) impact on the immune effects especially to carry out this study. [Method] Elsie the piglets grew up 30, based on a single factor randomized design is divided into six experimental treatments, according to the experimental design, divided into three groups of pigs inoculated with vaccines of different companies at the same time in each experimental pig The group is divided into feed Oldman, plus a No. 1 and not Gao was Man No. 1 kept the two control groups. Prior feeding 5d after weighing the first time weighing the end of the trial period, and the amount of feed record weight, feed conversion calculated the average of the six groups in the trial. Blue ear disease attenuated vaccine dose 2mL / head test cycle for 40d. Clinical response observed after vaccination and the determination of vaccination after vaccination 6d to 32d pig production performance. In grouped 1d, 22d and 32d vena cava blood, determination of blood biochemical indicators and antibody levels. [Results] (1) A group of piglets during pig blue-ear disease attenuated vaccine: increased body temperature, accompanied by anorexia, lethargy, lack of energy, a sharp cry of clinical phenomena; (2) the experimental group and the control group production performance improved daily gain increased by 22%, 16% and 7% (P lt; 0.05), feed conversion rate increased 17%, 6%, 7% (P lt; 0.05); (3) SOD activity increased in the experimental group herd of serum CK activity of the experimental group significantly improved compared with the control group (P lt; 0.05). [Conclusion] only three swine blue ear disease attenuated vaccine A vaccine protection rate of pigs, the other two companies attenuated vaccine reached less than qualified immunity protection, resulting in the failure of herd immunity. While blue ear disease attenuated vaccine can cause herd immunity stress, reduce the herd production performance and feed utilization, use of immunostimulants can effectively alleviate the herd immunity stress, improve the production performance of pigs to enhance the the pigs immune function. The Oldman No. 1 best use of add 1%.

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CLC: > Agricultural Sciences > Livestock, animal medicine,hunting,silkworm,bee > Animal Medicine ( Veterinary Medicine) > Livestock, poultry, wildlife diseases > Livestock > Pig
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