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The test to mice fed different doses of daidzein and 7 - Ipriflavone, exploring its impact on the reproductive function of male animals and the possible mechanism. Daidzein sperm quality of male mice, testicular growth and testosterone levels impact study. 1. To the 45-day-old male mice fed 5mg daidzein / kg diet (n = 16), serum testosterone levels increased by 93.3% (P <0.01), sperm motility has increased 17.08% compared with the control group (P = 0.07) deformity reduce the rate of 18.87% (P <0.01), acrosome integrity rate of 16.23% (P <0.05), and to improve testicular weight of 21.2% (P <0.05). 2. Of daidzein fed 100mg / kg diet (n = 21), serum testosterone decreased by 14.58%, the difference was not significant (P> 0.05), sperm motility decreased by 8.17% (P> 0.05), testicular weight reduced by 13.37%, the malformation rate also declined, acrosome integrity rate, but the difference was not significant. 3. Of daidzein fed 1000mg / kg diet (n = 14), serum testosterone level decreased by 63.66% (P <0.001), sperm motility decreased 8.3% (P> 0.05), the rate of malformations and testicular weight did not change significantly. 7 - Ipriflavone sperm quality of male mice of testicular growth and testosterone levels. 1. To 45-day-old male mice fed 5mg 7 - Ipriflavone / kg diet (n = 14), sperm motility improve 25.3% (P <0.05), the malformation rate reduced by 20.58% (P <0.01) acrosome integrity increased by 20.69% (P <0.05). Serum testosterone increased by 27.28% (P <0.05), testicular weight increased by 15.67% (P <0.05). 2. Fed 100mg 7 - Ipriflavone / kg diet (n = 19), elevated testosterone levels by 37.55% (P = 0.057), but were slightly decreased sperm motility and testicular weight, malformation rate and acrosome the full rate is slightly higher, but the difference was not significant. 3. Fed different diets * Division G Huangtian \u0026 g ketone level the 1000mp 7 isopropoxy decreased 28.74 Alexandra <0.05), decreased the bad child survival rate and weight of the testicles, back to the malformation rate rises acrosome integrity rate increased slightly, but the difference was not significant. The test results show that the different doses of daidzein and 7 a isopropoxide tomb of isoflavones on reproductive function of male animals have different effects, add sing / kg diet can improve sperm quality, and promote the growth of the testicles, stimulate testosterone secretion; 1000mg / kg diet added was / suppress trend, but no toxic effects on the testicles. 7 Ipriflavone role of testosterone secretion weaker than daidzein, but stronger improve sperm quality in large 【beans flavonoids.
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