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Effects of FuFangYingBuPo on Blood IFN-γ and IL-2 and Blood The-dependent T-Lymphocytes of Cyclosphamide-immunosuppr-Essant Mice

Author: HuSong
Tutor: ZhangYuLiang；HeHao
School: Hunan College of Traditional Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: YingBuPo Cyclophosphamide immunosuppression IFN-γ IL-2 Blood thy-dependent T-lymphocytes
CLC: R285
Type: Master's thesis
Year: 2004
Downloads: 152
Quote: 2
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Abstract


Objective: To study the effects of FuFangYingBuPo on blood IFN-y and IL-2 and blood the-depedent T-lymphocytes of Cyclophosphamide immu-nnosuppressant miceMethods: The model of Cyclophosphamide-immunosuppressant mice were established and were randomly divided into 3 groups by home.The normal control group was treated with NS, and the other groups were treated with NS, FuFangYingBuPo, polysacc-haridi lentinus edodest respectively for 14 days. IFN-yand IL-2 in blood serum and the number of CD3+,CD4+andCD8+ cells of blood thy-dependent T-lymphocytesin Cyclophosphamide-immunosuppressant mice were observed by the techniques of ELISA and SABC respectively.Results: IFN-r and IL-2 in blood serum in the group treated withFuFangYingBuPo was higher than that in the model group, difference between two groups was significant(p <0. 05, p <0. 005 ); The number of CD3+ CD4+ CD8+ cells of blood thy-dependent T-lymphocytes group treated with FuFangYingBuPo was higher than that in the model group, difference between two groups was significant ( p <0. 005).Conclusion: FuFangYingBuPo can enhance IFN-r and IL-2 in blood serum of Cyclophosphamide-immunosuppressant mice, and improve the number of CD3+, CD4+, CD8+ cells of blood thy-dependent T-lymphocytes in Cyclophosphamide-immunosuppressant mice.

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