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Objective To observe the Jianpiyishenfang Turbid to improve chronic renal failure ( turbid damp ) gastrointestinal symptoms in patients with clinical efficacy, and to explore the possible mechanism of action . Methods 40 patients met the inclusion criteria were randomly divided into 20 cases of 20 cases of the control group ( western medicine alone ) and treatment group ( having the spleen kidney Xiezhuo efficacy of Chinese medicinal herbs ) , the treatment lasted 1 month observed before and after treatment TCM syndrome score , gastric electrical amplitude , serum creatinine, blood urea nitrogen, blood lipids, changes in 24-hour urine protein . Using the the medical statistical software SPSS16.0 statistical analysis . Results (1) two sets of integrated efficacy efficiency comparison , 90% of the treatment group , 60% of the control group , the treatment group than the control group ( P lt ; 0.05 ) ( 2 ) two sets of TCM syndromes efficiency comparison , 100% of the treatment group , 30% of the control group , the treatment group than the control group ( P lt ; 0.05 ) (3) two sets of TCM symptom scores than those before treatment ( P lt ; 0.05 ) After treatment, the results were statistically significant ( P lt ; 0.05 ) (4) the gastric electrical amplitude of the treatment group compared with before treatment was significantly higher ( P lt ; 0.05 ) , the control and treatment groups have the same trend , but before and after treatment was not statistically significant ( P gt ; 0.05 ) ; treatment group results were statistically significant ( P lt ; 0.05 ) . (5) treatment group, serum creatinine ( Scr ) , blood urea nitrogen ( BUN ) , low - density lipoprotein cholesterol ( LDL - C ) , serum total cholesterol ( CHO ) , triglyceride ( TG ) , 24 - hour urine protein quantification ( Upro ) than before treatment decreased significantly ( P lt ; 0.05 ) ; control group and the treatment group have the same trend , but before and after treatment was not statistically significant ( P gt ; 0.05 ) ; after treatment, the results were statistically significant ( P lt ; 0.05 ) . (6) the treatment group and the control group of high-density lipoprotein cholesterol ( HDL - C ) than before treatment increased, but the two groups before and after treatment were not statistically significant ( P gt ; 0.05 ) ; After treatment, compared to the results was not statistically significant ( P gt ; 0.05 ) Conclusion on the basis of chronic renal failure ( CRF ) in the treatment of Western norms , the Turbid Jianpiyishenfang can significantly improve the CRF ( turbid damp ) in patients with gastrointestinal symptoms . The mechanism may be increased gastric electrical amplitude , enhance gastric motility, lower serum creatinine , blood urea nitrogen , urine protein , regulate blood lipids .
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