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Objective: To observe the circulation heartache capsules angina pectoris ( , blood stasis and qi stagnation ) the degree of patients with angina pectoris , ECG , blood rheology and efficacy of nitroglycerin stopped by the rate of its treatment of angina pectoris ( Blood \u0026 gas stagnation ) to make a preliminary evaluation of safety and efficacy , and to provide a basis for the III clinical trials carried out smoothly . Methods: A randomized , double-blind , parallel to the positive drug controlled trials . Select from June 2006 to December 2006 , the First Affiliated Hospital of Heilongjiang University of Chinese Medicine , medical clinics and wards of angina pectoris ( Blood \u0026 gas stagnation ) patients met the inclusion criteria and signed informed consent in 60 cases . Were randomly divided into experimental and control groups , 30 in each group , according to the order in which they were enrolled issuing the corresponding order drugs numbered drugs . The test group was treated with circulation heartache capsule 3 / time, 3 times / day ; control group was treated heart-protecting capsules , 3 / time, 3 times / day . The course of treatment was 28 days. Observed for 28 days after the two groups of patients with angina pectoris, electrocardiogram, blood rheology and nitroglycerin stopped by the rate of efficacy . Results: the treatment of angina pectoris angina ( , blood stasis and qi stagnation ) patients of the experimental group total effective rate was 83.33 % , effective rate is 30% ; control group total effective rate was 76.67% , effective rate is 33.33% . ECG to improve test group total effective rate was 76.67% , effective rate is 13.33% ; ECG improvement of the control group, the total effective rate was 73.33% , effective rate is 23.33% . Experimental group nitroglycerin stopped by 33.33 % in the control group was 30% . The experimental group and the control group , P gt ; 0.05 by statistical analysis meaningless. Hemorheology group comparison: the two groups before and after the test the hemorheology P lt ; 0.05 statistically significant ; between the two groups : two groups of blood rheology indicators before and after the test P gt ; 0.05 , not statistically significant . Conclusions : circulation heartache capsules can significantly improve coronary heart disease , angina and blood stasis and qi stagnation symptoms of patients with angina pectoris , ischemic electrocardiographic extent , hemorheology , effectively reducing the amount of nitroglycerin and efficacy with the control group drug insurance Xin Ning capsule quite . Clinical trials before and after security checks without exception, found no toxic side effects .
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