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Malt treatment of hyperprolactinemia and heather vine quality standard of

Author: WeiAnHua
Tutor: RuanJinLan
School: Huazhong University of Science and Technology
Course: Pharmacognosy
Keywords: Malt Hyperprolactinemia Heather vine Quality standards Aristololactam HPLC-UV
CLC: R259
Type: Master's thesis
Year: 2009
Downloads: 71
Quote: 0
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Abstract


Hyperprolactinemia (HPRL) is a variety of causes in vivo prolactin (PRL) levels caused by a group of syndromes, clinical manifestations of galactorrhea, amenorrhea, menstrual scarce, getting fat, infertility, anovulation, etc. [1 However, side effects of these drugs and the price is more expensive, so poor patient compliance. Malt is commonly used in clinical medicine blindly medicine, a line of gas digestion, spleen appetizer, the role of consumer inflation back milk, malt compound commonly used in clinical medicine to treat hyperprolactinemia, and single-malt flavor decoction to treat the disease pre-clinical observations also made satisfactory results, so the present study will further study the malt for the treatment of hyperprolactinemia in order to determine the malt treatment of the disease or the active site of the active ingredient, the malt developed into an inexpensive, effective The exact new Chinese medicine, instead of bromocriptine, changing mainly rely on expensive imported drugs bromocriptine treatment of hyperprolactinemia situation. for the control group, with a total malt extract high, medium and low-dose gavage treatment with radioimmunoassay modeling before and after the last administration in mouse serum prolactin levels, the statistical software to analyze the results. The results showed that the total malt extract high, medium and low-dose female mice could significantly reduce serum prolactin levels (P lt; 0.05), inhibition of metoclopramide-induced hyperprolactinemia, a considerable role and bromocriptine. And this study, phenol - sulfuric acid method for the determination of the sugar content in the extract; using UV spectrophotometry extract flavonoids. (2) Alkaline extract of malt Hyperprolactinemia Prolactin levels in female mice: the use of (a) the method of alkaline extract of malt to give high, medium and low-dose treatment, results indicate alkaline extract of malt high, medium and low-dose female mice could significantly reduce serum prolactin levels (P lt; 0.05), prompt treatment of hyperprolactinemia malt active site may be alkaline malt site. Heather vine of the genus Photinia pepper pepper vine Branch (Piper wallichii) dried leaves and vine stems or the whole plant. Of tepid, taste hard, have rheumatism, meridian, strong waist and knee, analgesic effect. With Qufeng, kidney yang, cough and asthma, blood analgesic efficacy [3]. The experiments on different batches of heather vine medicinal properties, microscopic characteristics are described, for heather vine extract, total ash, acid insoluble ash and moisture were determined, and its active ingredient, long pepper Mingning alkali (piperlonguminine ) conducted a qualitative identification TLC and HPLC quantitative research. Results heather vine developed quality control standards for the development and utilization of medicinal plants provide a scientific basis, laid the foundation for the development of new drugs. ingredient content is very necessary. In this study, HPLC-UV method for the simultaneous determination of different batches of three herbs heather vine aristololactam content, improve the basic quality standards heather vine herbs, medicinal herbs and traditional Chinese medicine for quality control and toxicity studies lay a material basis.

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CLC: > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases
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