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Study on Measurement of Artery Stiffness Based on Digital Volume Pulse Wave
Author: LiuYunLi
Tutor: JiangChengZhi
School: Tianjin University
Course: Measuring Technology and Instruments
Keywords: Photoplethysmography Arteriosclerosis Transmission and reflection Arterial stiffness
CLC: R318.51
Type: Master's thesis
Year: 2005
Downloads: 256
Quote: 4
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Abstract
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Cardiovascular disease is one of the serious diseases that endanger human health, the World Health Organization has listed as the number one killer of harm to human health in the 21st century. The nature of cardiovascular disease is an abnormal vascular structure and function. Early detection of subclinical vascular disease patients, and effective intervention through early detection of arterial stiffness and aortic function helps to have important academic value and social significance. Currently available to the non-invasive evaluation of arterial function methods have their own advantages and disadvantages, and there are many shortcomings expensive, complex operation, inadequate theoretical basis. Photoplethysmography plethysmography is a simple, low cost, and there is a huge potential for development. Therefore, this paper application fingertip photoplethysmography (DVP) method of evaluation of large artery hardness, that is, through the analysis of the DVP waveform information to calculate arterial stiffness. The purpose of the paper is to study the feasibility of the method. Papers from both theoretical and experimental study of the feasibility of the method. In theory, the details of the generation mechanism of pulse wave wall after the change in the structure of the arterial wall and atherosclerosis, the quality of the relationship of pulse wave velocity and arterial pulse wave propagation in arteries and reflection principle, the system reveals DVP waveform theoretical basis for the measurement of arterial stiffness. For experimental verification, we have developed measurement system based on the principle of arterial stiffness. This paper describes the system's hardware and software design. The hardware design focuses on the pulse wave detection circuit, software design focus on the data processing program. The whole system is based on the virtual instrument detection platform. Virtual instrument is easy to modify, the advantages of a short development cycle, greatly shorten the design cycle of the instrument. The repeatability experiments show that the system has high repeatability, and can be used for the feasibility study of the measurement of arterial stiffness. Finally, we were given the conclusion of the feasibility of the method. Experimental content including the selection of the two parts of the measurement conditions as well as the feasibility of experiments. The waveform differences by first comparing different measurement conditions, to determine the appropriate measurement conditions; then select the standard instrument, at the same time using the arterial system of the two instrument evaluation experimenter. Analysis and comparison of a sample of 33 cases experimenter, found between the results of the system with the standard instrument measuring the correlation coefficient of 0.63, both significantly correlated. In addition, we discuss the impact of age, gender, etc. on the the DVP waveform and arterial stiffness, results show different due to age, gender, DVP waveform showing different characteristics, arterial stiffness also will be different. Therefore, this method is a simple and accurate measurement of arterial stiffness. In this paper, the application DVP waveform measurement of arterial stiffness, both from the theoretical and experimental validation of its feasibility, and provides a simple and effective means for the prevention of atherosclerosis.
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