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Effect of Controlled Ovarian Hyperstimulation on Expression of Aquaporin-3 in Mouse Oocytes Using Semi-quantitative Real-time PCR Analysis

Author: MengQingXia
Tutor: HuangHeFeng;ZhangZhiFen
School: Zhejiang University
Course: Obstetrics and Gynaecology
Keywords: Aquaporin (AQP) Controlled ovarian hyperstimulation (COH) Oocytes In vitro fertilization (IVF) Real-time PCR
CLC: R714.8
Type: Master's thesis
Year: 2006
Downloads: 93
Quote: 0
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Abstract


Background aquaporin (Aquaporin, AQP) is mediated by water molecules in vivo transfer of life is very important to a transmembrane protein . In recent years, studies have shown that AQP widely distributed in various tissues and organs of mammals , selective and efficient completion of the water transport . Reproductive process related to a plurality of liquid changes, such as follicle maturation , embryo development, spermatogenesis , sperm formation , with the body of liquid secretion and reabsorption are closely related. Numerous studies have shown a variety of AQP abundantly expressed in the testis , sperm , follicle , uterus, placenta, fetal membranes and other tissues . AQP and Medical assisted reproductive cells stored in the relationship , it makes sense to research , because in gamete and embryo cryopreservation and thawing , it is water and other solutes through the plasma membrane of molecular pathways . Therefore, the study of the expression of AQP in the reproductive system , the role and mechanism of action has important physiological significance . Controlled ovarian hyperstimulation (Controlled Ovarian Hyperstimulation, COH) is widely used in assisted reproductive technology (assisted reproductive techniques, ART) , you can successfully get more mature eggs for IVF (in vitro fertilization and embryo transfer , IVF-ET). Studies have found that large doses of drugs that can cause ovulation in vitro by mammalian gametes

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CLC: > Medicine, health > Obstetrics and Gynaecology > Obstetrics
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