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Objective:To investigate the correlation between the left ventricular electomechanical dyssynchronism and mitral regurgitation in patients with heart failure by echocardiography, and find what factor influence the left ventricular electomechanical dissynchronism.Methods: Fourty patients with CHF (sinus rhythm,QRS≤120ms), including 18 patients with dilated cardiomyopathy (DCM) and 22 patients with eschemic cardiomyopathy (ICM). The values of these patients were compared with sixteen aged-matched heathy individuals. According to the electromechanical dispersion time in systolic phase >50ms,put these patients into two groups (groupⅠand groupⅡ). Using 2-dimentional guide M-mode, pulse wave and TDI, transthoracic echocardiograms was recorded at rest and each stages of dobutamine infusion by HP Sonos 5500 color echocardiographic diagnostic system. We acquired left ventricular ejective fraction (LVEF), the peak velocity of early diastolic (Ev), Ev deceleration time (EDT), the atrial systolic transmitral flow (Av), Ev/Av, transmitral flow tracing (MVTI), mitral regurgitation areas and mitral regurgitation duration(MRT). From the echocardiography apical four-chamber and apical two-chamber views, the activities of the mitral annulus were recorded by TDI at four positions (septal, lateral, anterior and posterior wall). We measured the peak systolic velocity (S), the peak early diastolic velocity (E), and the atrial systolic wall motion velocity (A), and calculated the means of S, E, A(Sm, Em, Am). Systolic and diastolic electromechanical dispersion were derived
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