MR-PWI, MR-DWI and MRS in differentiating benign from malignant bone tumors and tumor-like lesions.Materials and Methods: MR-PWI " />
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Functional MR Imaging in Diagnosing Bone Tumors and Tumor-like Lesions

Author: SunMeiYu
Tutor: WangShaoWu
School: Dalian Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: bone tumor MR-PWI MR-DWI MRS MR
CLC: R445.2
Type: Master's thesis
Year: 2006
Downloads: 113
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Abstract


Objective: To assess the diagnostic potential of MR-PWI' dissertation">MR-PWI, MR-DWI and MRS in differentiating benign from malignant bone tumors and tumor-like lesions.Materials and Methods: MR-PWI and MR-DWI were performed on 39 patients, and 18 patients underwent MRS using a GE signa 1.5T MR/I with a body/surface coil. The methods were as followed:1. MR-PWI: A bolus of gadopentetate dimeglumine (0.2 ml/kg body weight) was rapidly administered by means of a power injector with an injection rate of 2.5 ml/s through intravenous catheter in right or left antecubital vein. The perfusion imaging was started with GRE-EPI sequence as soon as the injection of the contrast medium commenced. Signal intensities were measured on delineated ROI and TIC was gotten using the functool 2 software system. Type of TIC, signal decreasing in first-pass period, maximum slope of TIC and signal difference between two standard states were compared between benign and malignant bone lesions. BV, MTT and BF were also compared.2. MR-DWI: With b value of 165 s/mm2、300 s/mm2、600 s/mm2、1000 s/mm2, imaging were performed with SE-EPI fast scan sequence with diffusion in three directions. ADC values were obtained and compared on delineated ROI using the functool 2 software system.3. MRS: Surface coil was selected and spectra for each volume of interest were acquired by using point-resolved surface coil spectroscopy sequence. Select ROI on metabolism-anatomy chart and obtain the MR spectroscopic data with Functool 2 software, including value of Cho, Cr, Lip and Ch/Cr ratio.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Magnetic resonance imaging
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