Dissertation > Excellent graduate degree dissertation topics show

High-frequency Ultrasound in Evaluation on Impact of Glycosylated Hemoglobin to Carotid Intima-medial Thickness and Remodeling of Carotid Atherosclerosis for Type 2 Diabetes Mellitus Patients

Author: JiaoJian
Tutor: ZhangYuHong
School: Dalian Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: Diabetes mellitus Carotid arteries Intima-medial thickness Glycosylated hemoglobin Ultrasonography
CLC: R445.1
Type: Master's thesis
Year: 2011
Downloads: 10
Quote: 0
Read: Download Dissertation

Abstract


Objective:To observe the impact of glycosylated hemoglobin (HbA1c) on intima-medial thickness (IMT) of carotid and remodeling of carotid atherosclerosis in type 2 diabetes mellitus (T2DM) patients with high-frequency ultrasound.Methods:A total of 100 patients with T2DM were divided into two groups according to the level of HbA1c, including 51 with HbA1c level less than 9% in group A and 49 with HbA1c level greater than or equal to 9% in group B Meanwhile,50 healthy subjects were enrolled in group C as normal controls. All T2DM patients and healthy subjects were examined with high-frequency ultrasound. The IMT of carotid, total vessel area (TVA) and lumen area (LA) of the vessels in which atherosclerotic plaque could be found were measured, while the remodeling index (RI) and the total plaque score were calculated. Moreover, the detection of HbA1c was performed, and the relationship between HbA1c and carotid IMT was analyzed.Results:The IMT of the trunk, bifurcation site of common carotid artery, the internal carotid artery,the average IMT and the total plaque score in group A and B were higher than those in group C (all P<0.05). The IMT and the total plaque score in group B was higher than those in group B (all P<0.05). Positive correlation was observed between HbA1c and the average IMT in group A and B (P<0.05).The remodeling rate of carotid atherosclerosis in group A and B was higher than that in group C(P<0.05).There was no statistical difference of remodeling rate between group A and B.The negative remodeling rate of group B was higher than those of group A and C (P<0.05),while no statistical difference was found in group A and C. The rate of positive remodeling was higher than that of negative remodeling in group A and C (all P< 0.05),while the rate of negative remodeling was higher than that of positive remodeling in group B (P<0.05).Conclusion :In T2DM patients,HbA1c is closely correlated with carotid IMT,and the remodeling of carotid atherosclerosis is influenced by HbA1c. High-frequency ultrasound is a convenient and precise method in assessing the the impact of HbA1c on IMT of carotid and remodeling of carotid atherosclerosis in T2DM patients.

Related Dissertations

  1. A Study of the Relationship between Ultrasound Images of Masicatory Muscle and Caraniofical Morphlogy of Young Males with Nomal Occlusion,R783.5
  2. Correlation Analysis between Coronary Lesion Severity and Peripheral Blood Cell CD34~+ Ratio in the Coronary Heart Disease Patients Complicating Diabetes Mellitus,R541.4
  3. Relationship between Carotid Artery Atherosclerosis and Coronary Artery Lesion in Patients with Coronary Heart Disease,R541.4
  4. Analysis of Related Factors and Outcomes of Gestational Diabetes Mellitus between Different Nationalities in Xinjiang,R714.256
  5. Risk Factors and Their Interaction of Type 2 Diabetes Mellitus among Rural Residents in Wang Cheng,R587.1
  6. Effects of New Intravenous Infusions on Blood Glucose Variability in Elderly Type 2 Diabetic Patients,R587.1
  7. Clinical Features of Type Ⅱ Diabetes Patients with Chronic Total Occlusion and Prognostic Study and Intervention,R587.1
  8. Prognostic Value of Hemogologbin Alc in Patients with Acute Coronary Syndrome,R541.4
  9. Study of Relationship between the Enhancement Type on Contrast-enhanced Ultrasonography and the Effect of High Intensity Focused Ultrasound in the Treatment of Hysteromyoma,R445.1
  10. Zi Yi Fang treatment of type 2 diabetes and dyslipidemia clinical observation,R259
  11. The Clinical Related Risk Factor Analysis of Diabetic Retinopathy,R774.1
  12. The Effects of Drag-reducing Polymers on Hemodynamic Parameters of Abdominal Aorta and Hindlimb Arteries and Microcirculational Perfusion of Rat Skeletal Muscle,R543
  13. Application Study of Constrast-enhanced Ultrasound in Deep Venous Thrombosis of Cnemis after Stork,R445.1
  14. Experimental Study of Regeneration After Closed Liver Trauma in Rabbits by Contrast-enhanced Ultrasonography,R445.1
  15. The Preliminary Clinical Study of Ultrasound Elasticity Imaging Technology to Evaluate the Elasticity Changes of the Deep Vein Thrombosis in Different Stages,R445.1
  16. A Study on Association between the Adiponectin Genotypes at Position 276 of Diabetes Mellitus with Carotid Atherosclerosis and Long-term Oxidative Stress,R543.4
  17. Epidemiologic Investigation of Glucose Metabolism Disorder in Shandong & Predictive Value on Glucose Metabolism Disorder with Anthropometic Parameters,R587.1
  18. The Clinical Study of Qu Yi Di Fang Combined with Metformin on Insulin Resistance of Type 2 Diabetes Mellitus,R587.1
  19. Therapeutic Effect of Quyidifang Combined with Metformin Hydrochloride on the Serum Level of IL-6 in Insulin Resistance in Type 2 Diabetes Mullitus,R587.1
  20. The Relevance Study of Metabolic Syndrome and Intima-media Thickness (IMT) of Carotid Artery in Han、 Uighur、and Kazakh Population of Xinjiang,R589
  21. Clinical Study on Shiweijiangtangtiaozhiyin in Treating Type 2 Diabetes Mellitus Associated with Hyperlipemia,R259

CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis
© 2012 www.DissertationTopic.Net  Mobile