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Investigation and Basic Experiments for Liquid CO2 Cryoprobe

Author: XuGuangCai
Tutor: TongMingWei
School: Chongqing University
Course: Refrigeration and Cryogenic Engineering
Keywords: Biological tissue cryoprobe liquid carbon dioxide cryosurgery vacuum
CLC: TH775
Type: Master's thesis
Year: 2006
Downloads: 33
Quote: 0
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The investigation on the theory of heat and mass transmission has been the hot research.The study of the heat and mass conductivity in the process, that biological tissue is frozen and thawed, has the signify theory meaning and practicality value.Aiming at the theory of heat and mass transmission, this thesis has done some analysis in theory and primary experiments. Firstly, we have done the analysis of The effects of the vacuum acting on blood flow perfusion. It indicates that blood flow perfusion has great infection on heat transfer in the biological tissue. According to the experiments, the time that the vacuum acts on biological tissue has little action for the engorgement and gore. The degree of the vacuum plays an important role on the engorgement and gore. The vacuum acting on the biological tissue can not only reduce the blood flow perfusion, but also lessen the pervasion of cancer cell. The probability that operation succeeds increases. So we design the liquid carbon dioxide cryoprobe with the vacuum structure.On the base, the author designs three structures: in vacuum, heat conduction and spout and makes the experiment device of the cryoprobe system. After repeating experiment, dry ice jam is overcome via adding a mid-heater. Therefore liquid CO2 avoids gas-solid multiphase flow, and supplies continuous low temperature gas for cryoprobe.Experimental results show that the 2-dimension temperature distribution for the first time, it includes:(1) The cooling velocity and freezing zone increases along the flux up at certain size of the cryoprobe in the same biological tissue.(2) As the diameter of cryoprobe increases, the temperature will descend faster, freezing zone will be broader obviously, and ice ball become larger. Until it arrives heat balance, the temperature keeps invariability.(3) Single freezing-thaw results in biggish mechanical injury already for loosen tissue such as pork liver; Successive freeze-thaw circle could quicken freezing and thaw velocity for compact tissue, and it has proved the more mechanical injury of successive freeze-thaw circle than the single freezing-thaw treatment.(4) Spout cryoprobe use less liquid CO2 than conductive cryoprobe.The paper shows that this cryoprobe has better cure effective. Synchronous gets the growth velocity and diameter character of ice ball in different biological tissue along the

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CLC: > Industrial Technology > Machinery and Instrument Industry > Instruments, meters > Medical and health devices > Freezer equipment for medical
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