Dissertation > Excellent graduate degree dissertation topics show
Expression of Transgelin Gene in Myoma of Uterus and Its Clinical Significance
Author: LiuQun
Tutor: WangMin
School: China Medical University
Course: Obstetrics and Gynaecology
Keywords: Transgelin expression uterine myoma suppression factor
CLC: R737.33
Type: Master's thesis
Year: 2006
Downloads: 102
Quote: 0
Read: Download Dissertation
Abstract
|
ObjectiveUterus myoma is the most common benign tumor in female reproductive organs. It is present in 20～30% of reproductive-age women. It is 52% of benign tumor in female reproductive organs. The exact etiology and mechanism is unknown.Transgelin gene was found for the first time as a transformation and shape-change sensitive actin gelling protein in fibroblasts and smooth muscle. It was considered as the marker gene of VSMC. The results of some researches indicated that expression of transgelin gene is low in cancer of bladder, breast, kidney, colon and ovary, and is normal in their control groups. Transgelin’s expression is very high in vascular smooth muscle tissue, and it located in cytoskele-ton. Therefore, we considered that Transgelin maybe related with genesis and progession of uterine myoma.To investigate the expression of Transgelin in uterine myoma tissue and to reveal its role in genesis and progression of uterine myoma, which will provide a theoretical basis for new conservative means to treat uterine myoma.MethodsThirty patients undergoing surgery for myoma of uterus and ten patients undergoing surgery for uterine prolapse at the shengjing Hospital of China Medical University from Aug to Dec 2005 were examined. Fresh samples of myoma tissue
|
Related Dissertations
- Research on Combinatorial Regulation of Multiple Transcription Factors,Q78
- The Research of the High-Rise Building’s Form and Expression in the New Century,TU971
- Research on Design of Teaching Buildings for Arts Departments of Higher Learning Institutions,TU244.3
- Expression of D-AtCGS in E. Coli and Preparation of Polyclonal Antibody Against D-AtCGS,Q943.2
- cDNA Cloning, Expression of vp5 and vp7 Genes and Subcecullar Localization of VP5 and VP7 Proteins in Grass Carp Reovirus,S941.41
- Expression of Prolyl Isomerase Pin1 in Osteosarcoma and the Effect of Regulation on Cell Cycle,R738.1
- The Expression Survey of BMP Signalling Pathway in the Human Embryonic Tooth Germ,R78
- Preliminary Study of Phosphorylation Effect on UGT1A3 Metabolism Activity Towards Drugs,R346
- Cloning and Expression of Growth Hormone Gene in Cobia (Rachycentron Canadus),Q786
- Cloning and Characterization of BAFF Gene from Whitespotted Catshark and Crucian Crap,S917.4
- Optimization of Fermentation Conditions, Purification, Cloning and Expression of a Cold-active Lipase from Pseudomonas Sp.RT-1,TQ925
- Comparative Study on Reproductive Biological Characteristics of Helicoverpa Armigera and Helicoverpa Assulta (Lepidoptera:Nuctuidae),S433
- GIH cDNA Cloning and Mrna Expression in Litopenaeus Vannamei,S917.4
- Cloning and Expression Analysis of Scavenger Receptor Class B Type Ⅰ and Antifreeze Proteinstype Ⅱ Genes in Lutjanus Sanguineus,S917.4
- Identification of B.melitensis 16M Protein Immunodominant Antigens,S852.61
- Establishment of Inderect ELISA for Detection of Antibodies Angainst STLV-1 and Preparation of Hybridoma Cell of Monoclonal Antibodies,R373
- Cloning and Expression of Xylanase Gene from Thermobifida Halotolerans YIM 90462~T,Q78
- Study on Synthesis and Physiological Function of N-carbamoyl-glutamate,R914
- Molecular Cloning, Mrna Expression and Rnai of Nadph-Cytochrome P450 Reductase Gene in Helicoverpa Armigera (Hǘbner),S435.622.3
- The Difference of Proteome Expression of Low Light Stress and Regular Light Recovery on Growth of Maize Seedling,S513
- Functional Analysis of Two Rice Nitrate Transporter Genes OsNRT1.1a and OsNRT1.1b,S511
CLC: > Medicine, health > Oncology > Genitourinary tumors > Female genital tumors > Uterine tumors
© 2012 www.DissertationTopic.Net Mobile
|