Dissertation > Excellent graduate degree dissertation topics show

Micro-Stimulator Design for Optic Nerve Visual Prosthesis in Artificial Vision

Author: WangJia
Tutor: RenQiuShi;ChaiXinYu
School: Shanghai Jiaotong University
Course: Biomedical Engineering
Keywords: Artificial vision Phosphene Visual prosthesis Optic nerve Nerve stimulator Microelectrode drive system
CLC: TH786
Type: Master's thesis
Year: 2007
Downloads: 134
Quote: 2
Read: Download Dissertation


According to the 2002 report of the World Health Organization , the global visual disability 140 million , of which 45 million for the blind . Of about 5.5 million blind people . Blinding There are many reasons , any period of : retina , optic nerve , visual cortex and other damage can lead to blindness in the visual pathway . Paragraphs in the visual pathway can produce visual sensation by electrical nerve stimulation , also known as phosphenes , it can pass a limited but important visual information , and restore basic vision to help the blind . In this paper , we propose a suitable optic nerve stimulation of the visual prosthesis multi- channel programmable implantable neurostimulator system design . This study include : First , electrical nerve stimulation theory : requirements analysis and design of the optic nerve stimulation parameters , provided the design basis and parameters for the microelectrode drive system in the optic nerve stimulator , and the establishment of a model of optic nerve stimulation ; programmable neurostimulator study : it is the core of the visual prosthesis device in accordance with its implementation , the microelectrode drive circuit design on two levels - ( 1) the use of analog integrated circuits , use CMOS devices configured micro- electrode driving circuit ; (2) using discrete components: digital to analog converter integrated circuit , a pressure flow converter IC , and the analog switch devices to form a micro - electrode driving circuit . Optic nerve stimulation can be realized transforming the image information captured by the CMOS camera , for the electrical stimulation signal is effective to stimulate the optic nerve , i.e. under control of the digital control terminal , the drive system of the micro-electrode can produce multi-channel charge-balanced biphasic micro current pulse , pulse amplitude range 10μA to 1 mA, a pulse width of 20 μsec to 400 μsec , the pulse frequency of 350 Hz or less . The innovation of this study is the use of a new method of electrical nerve stimulation , spiral cuff puncture electrode array implanted intraorbital segment of the optic nerve is located in the extracranial part . The main advantage of this stimulation method : ( 1) avoid craniotomy , may reduce the risk of surgery ; (2) the front of the visual pathway dysfunction can be corrected ; ( 3 ) can cover the entire field of view . The main difficulty is to study the visual formation and conduction mechanism and visual information encoding and signal processing to achieve the above functions .

Related Dissertations

  1. Research on the Influence of 3d Electric Field on the Excitability of the Optic Nerve,R318.0
  2. Study on the Effect of CNTF/LIF on Lens Injury Promoting the Regeneration of RGCs in Rats,R779.1
  3. Research and Testing System on Flexible Microelectrode Arrays of Epiretinal Prosthesis,R318.0
  4. Observe Puerarire Notoginseng Ginkgo Pharmaceutis Curative Protective Effect of the Therapeutic for Glaucomatous Optic Atrophy,R285.5
  5. Pathological and Functional Changes Following Optic Nerve Injury in Adult Cat,R779.1
  6. Experimental Study of the Effects of Acupuncture Treatment on Glaucomatous Optic Neuroprotection,R246
  7. Clinical Study of Combined Lumbar Plexus-Sciatic Nerve Block Using the Peripheral Nerve Stimulator,R614
  8. The Effect of Low-level Lead Exposure on the Retina and Optic Nerve from Rats during the Developmental Stage,R774
  9. Biological Characteristics of Oligodendrocyte Lineage Cells and Their Neuroprotective Effects,R329
  10. Studies on Changes of Primary Visual Cortex in Experimental Optic Nerve Injury Models,R779.1
  11. Recovery and Regeneration of the Optic Nerve Following Indirect Injury in Adult Rabbit,R779.1
  12. The Effects of Acupuncture-assisted Anesthesia in HANS Assisted Intravenous-inhalational General Anesthesia in Gynecologic Laparoscopy by Guide of AAI,R246.2
  13. The Comparison between Transpterional-sylvian and External Transethmo-sphenoid Decompression of Optic Canal,R651.1
  14. Preliminary Study on Nerve Stimulator,R-39
  15. Preliminary Study of Visual Function in a Rat Model of Experimental Autoimmune Encephalomyelitis,R744
  16. Image Processing System Based on DSP for Visual Prostheses,TP274.2
  17. Research of Power and Data Wireless Transmission System for Visual Prosthesis,R318.1
  18. Protective Effect of Modified and Wild Type Acidic Fibroblast Growth Factor after Rat Optic Nerve Crush,R779.1
  19. Evoked Membrane Potential Change in Rat Optic Nerve Fibre: Computer Simulation,R319
  20. Transnasal Edoscopic Sphenoethmoidal Optic Nerve Decompression on 37 Eyes with Traumatic Optic Neuropathy,R765
  21. The Establisment of Traumatic Optic Neuropathy Animal Model,R-332

CLC: > Industrial Technology > Machinery and Instrument Industry > Instruments, meters > Medical and health devices > Ophthalmic equipment
© 2012 www.DissertationTopic.Net  Mobile