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Micro-Stimulator Design for Optic Nerve Visual Prosthesis in Artificial Vision

Author: WangJia
Tutor: RenQiuShi;ChaiXinYu
School: Shanghai Jiaotong University
Course: Biomedical Engineering
Keywords: Artificial vision Phosphene Visual prosthesis Optic nerve Nerve stimulator Microelectrode drive system
CLC: TH786
Type: Master's thesis
Year: 2007
Downloads: 134
Quote: 2
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Abstract


According to the 2002 report of the World Health Organization , the global visual disability 140 million , of which 45 million for the blind . Of about 5.5 million blind people . Blinding There are many reasons , any period of : retina , optic nerve , visual cortex and other damage can lead to blindness in the visual pathway . Paragraphs in the visual pathway can produce visual sensation by electrical nerve stimulation , also known as phosphenes , it can pass a limited but important visual information , and restore basic vision to help the blind . In this paper , we propose a suitable optic nerve stimulation of the visual prosthesis multi- channel programmable implantable neurostimulator system design . This study include : First , electrical nerve stimulation theory : requirements analysis and design of the optic nerve stimulation parameters , provided the design basis and parameters for the microelectrode drive system in the optic nerve stimulator , and the establishment of a model of optic nerve stimulation ; programmable neurostimulator study : it is the core of the visual prosthesis device in accordance with its implementation , the microelectrode drive circuit design on two levels - ( 1) the use of analog integrated circuits , use CMOS devices configured micro- electrode driving circuit ; (2) using discrete components: digital to analog converter integrated circuit , a pressure flow converter IC , and the analog switch devices to form a micro - electrode driving circuit . Optic nerve stimulation can be realized transforming the image information captured by the CMOS camera , for the electrical stimulation signal is effective to stimulate the optic nerve , i.e. under control of the digital control terminal , the drive system of the micro-electrode can produce multi-channel charge-balanced biphasic micro current pulse , pulse amplitude range 10μA to 1 mA, a pulse width of 20 μsec to 400 μsec , the pulse frequency of 350 Hz or less . The innovation of this study is the use of a new method of electrical nerve stimulation , spiral cuff puncture electrode array implanted intraorbital segment of the optic nerve is located in the extracranial part . The main advantage of this stimulation method : ( 1) avoid craniotomy , may reduce the risk of surgery ; (2) the front of the visual pathway dysfunction can be corrected ; ( 3 ) can cover the entire field of view . The main difficulty is to study the visual formation and conduction mechanism and visual information encoding and signal processing to achieve the above functions .

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