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Explore and Study on ABO Immunomagnetic Particle for Reverse Grouping

Author: TongJun
Tutor: ChenXia;LiYong
School: Jilin University
Course: Biological Engineering
Keywords: ABO blood group system Anti- stereotypes Immunomagnetic beads
CLC: R446.6
Type: Master's thesis
Year: 2007
Downloads: 99
Quote: 0
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Abstract


The subject application of nano- magnetic particles developed the reverse grouping erythrocyte membrane magnetization can substitute fresh red blood cells reagents, magnetic particles prepared by a qualified chemical co-precipitation , the iron content of about 70% , the chemical composition of the iron oxide tablets diameter of approximately 200nm, can be stored in the water ; for coated magnetic particles , the red cell membrane , its antigenic properties titer of 64 corresponding human serum antibody completely inhibited . The prepared reverse grouping reagent application in blood centers in the automation system , and the detection of 640 parts of a 98.3% accurate . In addition , about 1,500 copies of the clinical patient 's blood type tested and found to comply with anti- stereotypes rate was 97.2% in the laboratory . Preliminary view that the application of nano- magnetic particles developed reverse grouping of red cell membrane magnetization reagents can be used in clinical blood group anti stereotypes detection , can joint with automated detection against stereotypes applied to a large number of the ABO blood group system .

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CLC: > Medicine, health > Clinical > Diagnostics > Laboratory diagnosis > Immunology Examination
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