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The purpose of this project is to select allergic airway inflammation by copying the model of asthma , is closely related to a number of indicators , to conduct a more in-depth discussion on the mechanism of action of Zhichuan soup . Experimental pharmacology , pathology , radioimmunoassay , immunohistochemistry such methods , overall , cytokines , inflammatory mediators , tissue morphology , gene expression levels to explore the effect and mechanism of Zhichuan soup asthma model . The results show that the antiasthmatic the soup can significantly improve the the asthma model 's respiratory function ; significantly control the airway inflammation of asthma model , the mechanism of action and inhibition EOS chemotactic regulate Th1/Th2 cytokine balance related with TNF, ICAM-1 regulation relevant ; significantly lower AHR, mechanism of action and inhibition of inflammation -related . Description the antiasthmatic soup has obvious anti-inflammatory , regulate the immune response , through multi-channel , multi-link, multi-target blocking the airway inflammation occurred , and the development process .
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