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Epidemiological Survey of Prevalence of Nonalcoholic Fatty Liver Disease and Its Risk Factors in Civil Servant of Urumqi

Author: XueLi
Tutor: LiuJiWen;XiaoLin
School: Xinjiang Medical University
Course: Public Health
Keywords: Civil servants Non - alcoholic fatty liver disease Epidemiological survey Prevalence Risk factors
CLC: R575.5
Type: Master's thesis
Year: 2009
Downloads: 47
Quote: 0
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Abstract


Objective: To investigate the prevalence of Urumqi examination of the civil service health crowd of nonalcoholic fatty liver disease (NAFLD) biochemical indicators of risk factors. Methods: Survey January 2008 - August 2009, the First Affiliated Hospital of Xinjiang Medical University, Fourth Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region People's Hospital medical examination Urumqi, the administrative institutions of the civil service of 2074, the survey The content includes general information, blood biochemistry examination and liver real-time ultrasound. Results: Urumqi, the administrative institutions of civil servants healthy 2074, a total of 704 cases detected in patients with non-alcoholic fatty liver disease, the prevalence was 33.94%. Prevalence of male civil servants was 49.65%, 15.17% prevalence of female civil servants, men were significantly higher than women (P lt; 0.01); Han NAFLD prevalence rate of 33.37%, Uygur NAFLD prevalence rate of 40.78%, difference was statistically significant (P lt; 0.05), at the age of 50 medical groups in the Uygur and Han prevalence of NAFLD was no significant difference (P gt; 0.05), while the 50-year-old to 60-year-old Uighur NAFLD prevalence in Han (P lt; 0.05), Han and Uygur prevalence of NAFLD peak at 50-60 years of age; the NAFLD group of body mass index (BMI), systolic blood pressure, diastolic blood pressure, triglyceride (TG ), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), fasting plasma glucose (FPC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-Valley aminoacyl GGT (GGT), uric acid (UA), urea (BUN), creatinine (CRE) are significantly higher than that of the control group (all P lt; 0.05), high-density lipoprotein cholesterol (HDL-C) levels were significantly lower than the control group (P lt; 0.05); NAFLD and drinking and metabolic syndrome components analysis showed that drinking, overweight or obesity, hypertension, diabetes, dyslipidemia, metabolic disorders, and other factors associated with NAFLD (P lt; 0.01). By single factor Logistic regression analysis showed that gender, age, ethnicity, education level, job or level, often drinking, overweight or obese, glucose metabolism disorders, dyslipidemia, hypertension and other is Urumqi civil servants of NAFLD possible risk factors (P lt ; 0.20); Multivariate Logistic regression analysis showed that the prevalence of NAFLD risk factors according to the size of the OR values ??were drinking, overweight or obesity, dyslipidemia, diabetes, hypertension, age, low HDL-C office or level, male ( P lt; 0.10); ethnicity, education level, smoking less of NAFLD. Conclusion: Urumqi Civil healthy people nonalcoholic fatty liver high prevalence: dyslipidemia, obesity and its related multiple metabolic disorders and non-alcoholic fatty liver disease is closely related; GGT determination can be used as non-alcoholic fatty liver disease predictor.

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CLC: > Medicine, health > Internal Medicine > Digestive and abdominal diseases > Liver and gall bladder disease > Liver metabolic disorders
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