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Studies on Secondary Metabolites of the Mangrove Plant Pandanus Tectoris and Marine Fungus ZT6-11

Author: FengXianQi
Tutor: ZhongHuiMin
School: Qingdao University of Science and Technology
Course: Organic Chemistry
Keywords: Mangroves Pandanus Marine fungus Triolein Coniferyl aldehyde
CLC: R284
Type: Master's thesis
Year: 2010
Downloads: 46
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Abstract


The chemical composition of the system in order to find new bioactive ingredients from the edge of the ocean and marine organisms , collected from China's Hainan mangrove plant pandanus the tree Pandanus tectories and marine fungi ZT6 - 11 secondary metabolites . Separation means of conventional silica gel column chromatography ( CC ) , preparative thin layer chromatography ( PTLC ) , gel column chromatography and recrystallization from pandanus and marine secondary metabolites of fungi were isolated 21 monomer compounds. Using a variety of modern spectroscopy (1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC, IR, FAB-MS, UV , etc.) to determine the 16 compounds plane structure and stereochemistry . From mangrove plants pandanus tree isolated and identified 16 compounds , including a the aromatic compounds coniferaldehyde ( F10 ) , an alcohol compound Cetearyl Alcohol ( F12 ) the two esters F11 glycerol trioleate F13 Di - ISO - butyl phthalate , a terpene compound lupeo (lF4), as well as the 8 -steroidal compound Cholest - 4 - en- 3- one ( F1 ) and Ergosterol peroxide ( F2 ) ,24 - methylcholesterol ( F3 ) , ( 24R ) - ergosta -4,7,22-triene 3-one (F5), cholesterin (F6), β-sitostenone (F7), Daucosterol (F8), β-sitosterin (F9), compound F1-F7, F11-F13 are first from the species , otherwise the structure of the three compounds is still in the identification . Five compounds were isolated from the fermentation broth of the marine fungus ZT6 - 11 . Compound Z1 identification of dulcitol compound Z2 is a 7 -hydroxy - 2H -1 -Benzopyran -2 , 4 ( 3H ) - dione , Compound 3 as glycerol trioleate , Z4 , Z5 structure under identification .

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