Dissertation > Excellent graduate degree dissertation topics show

A Study on Heterocyclic Ketene Aminals and the Synthesis and Structural Characteristic of Its Derivatives

Author: YouJun
Tutor: LiuBo
School: Harbin University of Science and Technology
Course: Materials Physics and Chemistry
Keywords: Heterocyclic ketene shrink amine Synthesis method Reaction Mechanism
CLC: O626
Type: Master's thesis
Year: 2004
Downloads: 125
Quote: 1
Read: Download Dissertation


Heterocyclic enone condensing the amine is a very versatile synthon heterocyclic compound . Conducted a detailed study of the preparation , structural characteristics , and the reaction characteristics , and its application in organic synthesis , etc. condensed heterocyclic ketene amine . The in-depth study of this reaction is the main subject of this dissertation . This thesis work mainly include two parts : ( 1 ) systems studied of heterocyclic ketene condensing amine synthesis method , as well as heterocyclic ketene condensing amines with a series of nucleophilic addition reactions of electron deficient reagent ; (2) Synthesis the four novel heterocyclic ketene condensing amine derivative, and conducted a detailed analysis of their structure , the establishment of the new ways of the amine derivative of a synthetic heterocycloalkenyl . The first part : 1 . Detailed description of the latest of heterocyclic ketene reduction amine synthesis . Heterocyclic system shrink electrophilic addition reaction of amines : miscellaneous change ketene shrink amine is a unique hybrid ene component , with a series of α, β- unsaturated compounds , azo ester as well as activation the addition reaction of the carbonyl compound after azepin ethylenically way . Heteroaryl exchange ketene condensing amine as the two nucleophiles substituted reaction can occur regiospecific alkylation reaction , region selection acylation, glycosylation reaction , halogenation , nitration reaction . Cycloaddition reaction occurred with 1,3 - dipolar reagents . Heterocyclic ketene condensing the amine with a nitrile ylides reaction can only get 1:1 nucleophilic addition product , the nucleophilic reaction can occur at the α-carbon atom , to produce C- substituted product , can also occur in the heterocyclic secondary amine groups generated N-substituted product. Part II: enone condensing substituted heterocyclic amine with ethyl bromoacetate reaction fluorobenzoyl or heterocyclic aroyl , high yield diazabicyclo [ 330 ] or diazabicyclo [ 430 ] derivatives. The reaction mechanism was discussed in the text , and were used to characterize the structure of the product .

Related Dissertations

  1. Flexible,rigid,Synthesis and characterization of mixed ligand complexes,O621.1
  2. The Study on the Preparation of McAb to Anti-Melemine and Establishment of Ic-ELISA for Detetion of Melamine,S859.84
  3. Containing pyridyl group metal complexes Synthesis and Structure,O627
  4. Synthesis, Characterization and Application of the Novel Coordination Polymer with Pyridinecarboxylic Acid as Ligands,O633.5
  5. Theoretical Studies on the Mechanism of CO Catalytic Oxidation on Au Surfaces,O643.32
  6. The Study on Reaction Mechanism and Dynamics of MgO Preparation with Molten Salt,O614.22
  7. The different synthesis MgAlON powders and its oxidation behavior,O614.22
  8. Quantum Chemistry Study on the Reaction of CH2NOH with NOx(X=1,2),OH,O643.12
  9. Theoretical Study on the Reaction Mechanism of Butene Anions with N2O in Gas Phase,O643.12
  10. Study on the Preparation of Boron Powder and ZrB2 Powder by Combustion Synthesis and Formation Mechanisms of Them,TB383.3
  11. Study of the Reaction Mechanism of Ethylbenzene Dehydrogenation in the Presence of Carbon Dioxide,O621.2
  12. N-heptane HCCI combustion process temperature thermodynamics and kinetics theory,O643.21
  13. Robust Control System Design for Triaxial Air-bearing Turntable,TP273
  14. Several organic sulfur compounds in the atmosphere the reaction mechanism and thermodynamic properties of theoretical research,X13
  15. Study on Pesticide Wastewater Treatment Using O3/UV Process,X703
  16. Theoretical study of the H5N1 influenza virus enzyme catalyzes the hydrolysis of RNA reaction mechanism,O643.12
  17. Quantum Chemistry Study on the Reaction of HOSO with NO, OH, X(X=F,Cl,Br),O643.12
  18. Study on Component System State-space Model Synthesis Method,TH131
  19. Density Functional Theory Study on the Reaction of Three Types of Oxygen Carrier with CO in Chemical-Looping Combustion System,TK16
  20. Application in the Synthesizing Reaction Mechanism of Energetic Compounds by Multivariate Curve Resolution Combining On-line IR,O657.33
  21. Low grade silver copper -silver-copper flotation recovery test,TD952

CLC: > Mathematical sciences and chemical > Chemistry > Organic Chemistry > Heterocyclic compounds
© 2012 www.DissertationTopic.Net  Mobile