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Objective: observed kidney Ankun soup treatment of kidney yin and yang deficiency type peri - menopause syndrome clinical efficacy , and to explore its mechanism of action . Methods: 60 cases of kidney yin and yang type of perimenopausal syndrome were randomly divided into treatment group (30 cases , oral and kidney Ankun soup ) and the control group (30 cases , oral shenqi Immortals piece ) Changes in clinical symptoms, signs of improvement ; before and after treatment of estradiol ( E2 ) , follicle-stimulating hormone ( FSH ) , luteinizing hormone ( LH ) , total cholesterol ( TC ) , high density lipoprotein ( HDL ) , low density lipoprotein (LDL ) , catecholamine ( CA ) , epinephrine ( E ) , norepinephrine ( NE ) , parathyroid hormone ( PTH ) , calcitonin ( CT ) and other indicators of change . After treatment, the difference between the treatment group and the control group group . Results: the clinical efficacy of the treatment group and control group total effective rate was 93.34% and 70.00% , the difference between the two groups was significant ( P lt ; 0.05 ) ; the TCM syndromes total efficiency were 96.67% and 70.00 % , the difference between the two groups was significant ( P lt ; 0.05 ) ; treatment, the treatment group and the control group Kupperman , TCM symptom score before treatment , the difference was significant ( P lt ; 0.01 ) , the two groups The difference between the two was significant ( P lt ; 0.01 ) . Treatment, elevated in patients treated with E2 , FSH decreased , the difference was significant ( P lt ; 0.01 ) ; reduce TC , LDL , HDL increased , the difference was significant ( P lt ; 0.05 ) ; urinary CA , E , NE lower, the difference was significant ( P lt ; 0.05 ) lower ; PTH , CT pressure , the difference was significant ( P lt ; 0.05 ) After treatment in addition to LH indexes with the control group , the difference was significant ( P lt ; 0.01 , P lt ; 0.05 ) Conclusion: by kidney Ankun soup kidney yin and yang type of perimenopausal syndrome better therapeutic effect , its mechanism of action may be to improve the function of the hypothalamic - pituitary - ovarian axis to adjust the central neurotransmitter , improve blood lipids and bone metabolism and many other aspects .
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