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Preface metabolic syndrome (Metabolic syndrome, MS) is a clinical syndrome, lipid disorders, abdominal obesity and hypertension gathered one damage to the blood vessels of the heart and brain is the most important consequences of the large number of domestic and international epidemiology of MS The survey showed that, in different regions, ethnic and socio-economic situation This is mainly because its incidence is influenced by many genetic and environmental factors, in addition to by different diagnostic criteria affect the prevalence of MS. It is very necessary to conduct in-depth study of MS prevalence and risk factors in different regions. City MS prevalence is higher than in rural areas more than in the previous studies reported chronic diseases in rural areas, but in recent years, larger changes. Rural areas the prevalence of hypertension is higher than the national average, rural MS happens, what characteristics found in our survey still has been no clear conclusion. This study to select the rural areas of northern China, a larger sample size to investigate the prevalence of MS in a hypertension-prone areas, and analysis methods using multivariate analysis of influencing factors of MS and its relationship with cardiovascular and cerebrovascular diseases, and to understand the local farmers prevalence of MS, and to provide a preliminary basis for the development of control strategies and measures of the local MS. Subjects and methods, the choice of the object of study in the areas of Liaoning Province, a high incidence of hypertension Zhangwu County cluster multistage random sampling, randomly selected from a township in Zhangwu County, East, West, South, North, five regional total of five townships, including four townships were randomly selected two villages, a township randomly selected a village, a total of nine villages. Adult residents older than 20 years old in the village survey, a total survey of 4780 people, male 1798, female 2982, the age range of 20 to 84 years old. Survey content and detect indicators in the field to ask to fill out the questionnaire and measured way, the survey include: asking the general characteristics, smoking history, history of alcohol consumption, diet and the prevalence of the disease situation and the family members of patients with hypertension ; measurement of blood pressure, height, weight, and so on. Site per person lancing 5ml (overnight fasting), the serum was separated by centrifugation, packing frozen at -20 ° C for serum biochemical indicators detection. Third, diagnostic criteria and methods of measurement of metabolic syndrome diagnostic criteria, according to the 2004 China Diabetes Society of the Chinese Medical Association diagnostic standard (CDS): meet three of the following four components or all of: being overweight or obese: weight index (BMI) ≥ 25.0kg / m ~ 2; hyperglycemia: fasting plasma glucose ≥ 6.1mmol / L and (or) 2h postprandial blood glucose ≥ 7.8mmol / L and (or) has been diagnosed with diabetes and treatment; hypertension: systolic / diastolic blood pressure ≥ 140/90mmHg and (or) has been diagnosed with high blood pressure treatment; dyslipidemia: fasting triglyceride (TG) ≥ 1.7 mmol ╱ L (or fasting high-density lipoprotein (HDL-C) The) Male 0.9mMOL / L, women <1.0 mmol / L,. Blood pressure measurement by health care professionals to standardizing all measured under standard conditions. Biochemical indicators detected by the First Hospital of China Medical University laboratory responsible for completing Japan Chemical Company of Japan automatic biochemical analyzer 7150 type, blood sugar, triglycerides, HDL-C levels by colorimetric analysis. By the quality inspection entry microcomputer using SPSS software to establish a database; analytical methods used for x ~ 2 test, trend analysis and Logistic regression, with the investigation of the statistical analysis method analysis software SAS9.0, and statistically on a significant level predetermined for α = 0.05. China's 2000 census data on the prevalence of standardized. Results, the metabolic abnormalities ingredients and the population prevalence of the metabolic syndrome, metabolic components of metabolic abnormalities composition and metabolic syndrome of body mass index (BMI ≥ 25 kg / m 2) abnormal rate of 30.67%; abnormal blood pressure (systolic blood pressure ≥ 140mmHg or diastolic blood pressure ≥ 90 mmHg) was 47.09%, systolic blood pressure abnormalities (systolic blood pressure ≥ 140mmHg) rate of 39.33%, diastolic abnormalities (diastolic blood pressure 90 ≥ mmHg) rate of 37.85%; abnormal blood sugar (glucose ≥ 6.1 mmol / L) rate of 6.70%; abnormal triglycerides (fasting TG ≥ 1.7mmol / L) rate of 25.2%; high-density lipoprotein cholesterol In exception (fasting blood HDL-C men <0.9 mmol / L, women <1.0 mmol / L) rate of 2.1%. To metabolic abnormalities ingredients BMI in no significant difference between male and female prevalence, systolic blood pressure, diastolic blood pressure, blood glucose, TG statistically significant difference in the male and female prevalence were male prevalence than women, high density lipoprotein prevalence in men and women statistically significant, sick women than men. The prevalence of the metabolic syndrome in the investigation of the crowd of 524 people, the prevalence was 11.00%, the number of male patients was 231, prevalence rate of 12.8%, 9.8% of the 293 people, the prevalence of the number of sick women. The male and female prevalence significant difference in male patients than in women, after the 2000 national census data, the standardized metabolic syndrome prevalence was 16.43%. 2 the metabolic abnormalities ingredients and different age distribution of the metabolic syndrome metabolic abnormalities ingredients in BMI, systolic blood pressure, diastolic blood pressure, blood glucose, TG in the prevalence of different ages, there are statistically significant, and showed age metabolism The prevalence of abnormal components a growing trend. Metabolic abnormalities ingredients HDL-C was no significant difference in the prevalence of different ages, the no age abnormal metabolic components illness growing trend. Metabolic syndrome prevalence at different ages and different age metabolic syndrome increased the trend. 3, the metabolic abnormalities ingredients and ethnic distribution of the metabolic syndrome, the prevalence of metabolic abnormalities composition of all ethnic groups in the comparison, BMI and blood glucose, TG, HDL-C national prevalence was no significant difference in systolic blood pressure and diastolic blood pressure in prevalence between different ethnic groups, a significant exception of Han systolic blood pressure higher rate of 40.4%, the Manchu minimum 30.4%. Was no significant difference in the prevalence of the metabolic syndrome in various ethnic, all ethnic groups the prevalence of the metabolic syndrome was no difference. 4, metabolic abnormalities composition and geographical distribution of the metabolic syndrome the metabolic components abnormal rate comparison of the various townships, BMI, systolic and diastolic blood pressure, blood glucose, TG, HDL-C abnormal rate between the township, significant areas with high rate of abnormal BMI Hal sets of regions and 39.4%, systolic blood pressure abnormal rate of higher areas after the new autumn region is 47.5%, diastolic blood pressure and abnormal rate higher regions Zhanggutai region, 43.1%, abnormal blood sugar higher rate areas the Zhanggutai region, 8.1%, triglycerides abnormal higher rate of the region after the new autumn region, 31.1% of high-density lipoprotein abnormality higher rate areas the Zhanggutai 2.9%. The township the prevalence of the metabolic syndrome differences was statistically significant, which the region Zhanggutai metabolic syndrome prevalence highest rate of 13.6%. Second, univariate analysis of the metabolic syndrome risk factors in the case group and the control group as the dependent variable, metabolic syndrome risk factors as independent variables, the application of the chi-square test to analyze the relationship between the various factors and metabolic syndrome. In addition to smoking, drinking type, pickles, dosage, and other factors in coronary heart disease genetic history between the control group and the patient group have significant differences. The metabolic syndrome risk factors for non-conditional logistic regression analysis, the case and control groups based on univariate analysis, will test a statistically significant difference in the variable gender, age, alcohol consumption, hypertension genetic, hereditary cerebral hemorrhage, each The daily amount of salt into the non-conditional logistic regression model analysis. Age, sex, genetic hypertension, the daily salt with metabolic syndrome, age, male gender, hypertension, genetic, daily use of salt may be susceptible to risk factors of the metabolic syndrome. Suffering Stroke disease cases and control groups the prevalence of the metabolic syndrome metabolic syndrome suffered significant difference in disease with stroke patient group and the control group not suffering from stroke disease, suffered from stroke The case group the prevalence of the metabolic syndrome prompted the metabolic syndrome may be a risk factor for stroke. Five suffered from cases of coronary heart disease group and the control group, the prevalence of metabolic syndrome metabolic syndrome suffered significant difference in coronary heart disease in the case group and the control group not suffering from coronary heart disease, the risk of stroke cases relatively high prevalence of metabolic syndrome prompted the metabolic syndrome may be a risk factor for coronary heart disease. Sixth, the relationship between metabolic abnormalities the metabolic abnormalities ingredients with cardiovascular and cerebrovascular illness into scores with cerebral infarction, cerebral hemorrhage, cardiovascular and cerebrovascular number of diseases presents trend into metabolic abnormalities associated with the fractional increase the risk of cerebral infarction, cerebral hemorrhage, heart number of cerebrovascular disease also showed an increase and significant metabolic abnormalities into a score of 3, the possible impact on cardiovascular and cerebrovascular diseases. Discussion in recent years due to the change of eating habits, a large number of epidemiological investigations, the country metabolic syndrome prevalence is rising, the cause of cardiovascular disease was significantly increased, and the incidence of metabolic syndrome by many factors the impact, which include genetic and environmental factors, but also by the diagnostic criteria, and therefore very important to study the prevalence and impact of risk factors in different parts of the metabolic syndrome, and beneficial for the survey population to take appropriate intervention strategies and measures to reduce the prevalence of the metabolic syndrome, to reduce the incidence of cardiovascular and cerebrovascular diseases. 1, the prevalence of the metabolic syndrome in the investigation of metabolic syndrome prevalence was 11.00%, Hebei rural residents of metabolic syndrome prevalence was 14.2%, Zhongshan City, Guangdong Province, rural residents with metabolic syndrome prevalence 2.91% (CDS standard), the regional survey using different diagnostic criteria, in addition to standardized without population, and therefore not suitable for direct comparison. In the 2000 investigation of the metabolic syndrome (IDF criteria), the comparison of age-standardized prevalence of the metabolic syndrome, the the northern high prevalence in the south, the city's high prevalence in rural areas. Rate of abnormal blood pressure in men in the survey, the rate of glucose abnormalities, abnormal blood lipids, metabolic syndrome prevalence is higher than the female. In some studies, women the prevalence of the metabolic syndrome than men. Addition of all ages metabolic abnormalities composition, metabolic syndrome prevalence, the performance is higher than the low ages, and accompanied by the growth of the age there is an increasing trend in the prevalence of high prevalence of age, with a large Most studies have the same result. Analysis of the nation, in addition to the Han Chinese residents systolic and diastolic abnormalities higher in Manchu, Mongolian, of other metabolic components indicators and the metabolic syndrome prevalence between the Han, Manchu, Mongolian, there is no obvious difference between. Gathering of minorities in Xinjiang region, abnormal metabolic components of the Han Chinese residents of BMI, blood glucose, TG, and HDL-C index rate and the prevalence of the metabolic syndrome are higher than the local Mongolian residents. Games Township metabolic abnormalities ingredients and the prevalence of the metabolic syndrome analysis abnormal metabolism of ingredients and areas with high prevalence of metabolic syndrome should be carried out for different games Township metabolic abnormalities ingredients and the prevalence of metabolic syndrome nature of prevention. Second, during the analysis of the risk factors of the metabolic syndrome risk factors, including age, sex, and daily use of salt, hypertension genetic exhibit the risk factors of the metabolic syndrome. The growth of the age as the risk factors of the metabolic syndrome, and most of the research results. In this study, the male sex has become the metabolic syndrome risk factors, mainly due to the survey, men suffering from abnormal metabolic components rate and metabolic syndrome is higher in the results of the study of women, and Jian-Hua Jiang et al, the abroad study also showed that the prevalence of the metabolic syndrome women less than men because women have antioxidant protective effect of estradiol. Daily use of salt diet salt intake performance in previous studies have found that excessive salt intake is high blood pressure disease risk factors, hypertension is one of the components of metabolic syndrome, and research that salt intake, blood pressure mechanism can induce insulin resistance, insulin resistance, and to promote the progress of the complications of hypertension, in addition to insulin resistance leads to reduced insulin sensitivity, resulting in abnormal metabolism of carbohydrates and lipids. The metabolic abnormalities ingredients increased. Hypertension genetic risk factors of the metabolic syndrome, studies have shown that people with a family history of hypertension is high risk of metabolic syndrome. Therefore prompt parents party people suffering from high blood pressure are more likely to develop metabolic syndrome. The individual components of the metabolic syndrome are independent of each other and influence each other, about a certain area of ??the components of the metabolic syndrome and possible risk factors conducive to control the prevalence of metabolic syndrome and reduce the incidence of cardiovascular and cerebrovascular diseases. In the survey found that the major metabolic abnormalities ingredients for high blood pressure, high BMI, high TG, and should therefore be to strengthen the control of these factors reduce metabolic abnormalities ingredients and reduce the prevalence of the metabolic syndrome. Third, the diagnostic criteria for metabolic syndrome before most of the survey are based on the World Health Organization (WHO) and the U.S. National Cholesterol Education Program Adult Treatment Panel (NCEP-ATP Ⅲ) diagnostic criteria, diagnostic criteria proposed focus at a different angle. Both diagnostic criteria found in the country of the International Diabetes Federation (IDF) and the Chinese Diabetes Society (CDS) on the comparative analysis of the diagnostic criteria of the metabolic syndrome have better compliance rate (79.95%), two standard diagnosis of MS The rate of cardiovascular disease in patients with hair similar, indicating that the two standards can be used for the Chinese population, can well reflect the prevalence of the metabolic syndrome in Chinese residents. The metabolic syndrome and cardiovascular disease relationship found in the analysis of the metabolic syndrome prevalence of stroke, coronary heart disease cases and control groups, metabolic syndrome is a stroke, a risk factor for coronary heart disease and found associated with metabolic abnormalities as the fractional increase the risk of cerebral infarction, cerebral hemorrhage, also showed an increase in the number of cardiovascular and cerebrovascular diseases, so that the impact of metabolic syndrome on cardiovascular and cerebrovascular diseases, metabolic syndrome cohort study that patients with cardiovascular and cerebrovascular incidence was significantly higher than in patients not suffering from metabolic syndrome. The study main only preliminary study of possible risk factors, should further enhance the depth of the metabolic syndrome risk factors. Because the metabolic syndrome increases the incidence of cardiovascular and cerebrovascular diseases, it is necessary to continue to study the components of the metabolic syndrome factors of cardiovascular and cerebrovascular diseases are the biggest, this study did not explore this issue in depth, should be carried out metabolic abnormalities ingredients cohort study of patients with cardiovascular and cerebrovascular disease in patients with metabolic syndrome. Conclusions The results suggest that: Major metabolic abnormalities ingredients for body mass index, blood pressure, triglycerides. Age, male, daily use of salt, hypertension genetic susceptibility to metabolic syndrome risk factors. The metabolic syndrome and metabolic abnormalities ingredients may be a risk factor for cardiovascular and cerebrovascular diseases.
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