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Study on the Synthesis and Properties of New Materals and Their Application in Electroanalytical Chemistry

Author: WuShengJiang
Tutor: YeBaoXian;ZhaoBangTun
School: Zhengzhou University
Course: Analytical Chemistry
Keywords: TTF derivatives Synthesis and Characterization Electrochemical Properties Amphiphilic GO Colchicine
CLC: O621.2
Type: Master's thesis
Year: 2011
Downloads: 45
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Abstract


In recent years, with the development of supramolecular chemistry, molecular electronics research and in-depth, four-tetrathiafulvalene (TTF) unit due to its special electrochemical behavior, assembly features, easy derivatization features into macromolecules and supramolecular System important functional structural units. The synthesis of this thesis four kinds containing hydrophobic long chain alkane and a hydrophilic ether linkage thiadiazol amphiphilic TTF derivatives were characterized by a variety of means, and to determine its molecular structure. The synthesized TTF derivative electrochemical behavior and LB film-forming properties were studied. Chemically modified electrode is very hot research field of electrochemistry, electroanalytical chemistry. Graphene since its inception in 2004, has been in many other areas caused widespread concern, chemically modified electrode has been more and more attention because of its special nature. In this paper include the following: 1. Amphiphilic TTF derivatives synthesis and characterization of two - (1,3 - dithiole ene-2 ??- thione -4,5 - dithiolate) together zinc acid tetraethyl ammonium salt (Compound 1) are refluxed in acetonitrile and bromotetradecane bromooctadecane, synthesis of the corresponding 1,3 - dithiolane cyclopentene - 2 - thione (compound 4a and 4b). Triethyl phosphite as coupling agent, 4a, 4b, respectively, and the 4,5 - dinitrile ethylthio-1 ,3 - dithio cyclopentene -2 - one (Compound 3) Synthesis of cross-coupling reaction occurs two TTF derivative (compound 5a and 5b). In the presence of cesium hydroxide, 5a and 5b respectively, with 2 - iodo-ethoxy ethanol, the reaction of the two hydroxyl-containing derivative (Compound 6a and 6b), TTF. Triethylamine as acid binding agent, its reaction with methyl benzene sulfonyl chloride, the synthesis of two containing activated hydroxy TTF derivative (compound 7a and 7b). In the presence of sodium hydroxide, 7a and 7b were obtained with mercapto-thiadiazole reaction four containing hydrophobic long chain alkane and a hydrophilic ether linkage thiadiazole amphiphilic TTF derivative (Compound 8a-8d), and its 1HNMR, 13C NMR, IR, MS characterization. Electrochemical properties and film-forming properties of amphiphilic TTF derivatives studied own synthesis of four two pro TTF derivatives 8a-8d electrochemical properties and film-forming properties, discuss relevant groups to its electrochemical properties and film-forming properties. Its electrode kinetic parameters were measured using the appropriate electrochemical method. 3. The graphene oxide synthesis and synthesis of modified electrode graphite oxide ene (GO), and then build a new detection colchicine voltammetric sensors in the surface of the glassy carbon electrode GO-Nafion composite film. Colchicine concentration was detected in 0.1 mol L-1 H2SO4 base solution linear range of 5.0 × 10-8-2. 0 × 10-5mol L-1, the detection limit of 1.5 × 10-8molL-1. And the method is applied to real samples.

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CLC: > Mathematical sciences and chemical > Chemistry > Organic Chemistry > Organic Chemistry general issues > Properties of organic compounds
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