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Synthesis and Fluorescence Behavior of a Thermoresponsive Polymer Ended with Fluorescent Group
Author: GuoYanZhen
Tutor: LiHongPing
School: Zhengzhou University
Course: Physical and chemical
Keywords: Temperature-sensitive polymer Reversible addition - fragmentation chain transfer polymerization Poly - N- isopropyl acrylamide Fluorescent probe
CLC: O631.3
Type: Master's thesis
Year: 2011
Downloads: 63
Quote: 0
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Abstract
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In this thesis, synthesis temperature - sensitive polymer terminal fluorescent , and its fluorescence intensity with the temperature changes the nature of a preliminary study . On the one hand , through a series of simple organic reactions (including Knoevenagel reaction , Sonogashira reaction , Diels - Alder reaction ) synthesis of two novel fluorescent molecules 4 and 6 and NMR ( including 1H NMR , 13C NMR , 2D NMR ) infrared (FTIR) and mass spectrometry ( MS ) characterization confirmed its structure, while cultivating a single crystal of the two compounds , more intuitive has been successfully synthesized compounds 4 and 6 . After ethanol as solvent , the nature of the fluorescence (FL) and the light emitting performance of its ultraviolet-visible ( UV ) can be found in the conjugated structure of the compound 6 4 . On the other hand , in the living / controlled radical polymerization reversible addition - fragmentation chain transfer polymerization ( RAFT ) synthetic medium molecular weight and narrow molecular weight distribution poly - N- isopropyl acrylamide ( PNIPAM ) with magnetic resonance imaging ( 1H NMR ) , infrared (FTIR) and gel permeation chromatography (GPC) characterization of its structure and molecular weight . Then its end group functionalized with maleic anhydride ( MAH ) was successfully synthesized PNIPAM - MAH . Finally, the synthesis of PNIPAM -MAh with fluorescent molecules 4 and 6 at the same time carry out the acylation reaction , the successful synthesis of the end of the fluorescent temperature sensitive polymer PM- 6 , and its low critical solution temperature (LCST) and fluorescence the nature of the intensity varies with temperature . The temperature -sensitive polymer is expected to be applied as a temperature control switch in the drug delivery systems .
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CLC: > Mathematical sciences and chemical > Chemistry > Polymer chemistry ( polymer ) > Polymer physics and physical chemistry of polymers > The chemical nature of polymers
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