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Objective: To investigate thoracic surgery in our hospital from 2008 to 2010 admission of drug use and trends of chemotherapy in patients with malignant tumors, analysis of chemotherapy drugs, chemotherapy, adjuvant and other symptomatic support the reasonableness of the medication proposed to promote the rational use of drugs of clinical opinion, the tumor more safe and effective treatment of patients. Methods: A retrospective survey method, choose our hospital admission thoracic surgery from 2008 to 2010 and 112 patients receiving chemotherapy, a total of 412 cases as the research object. The basic patient access to medical records, disease, chemotherapy drugs, adjuvant chemotherapy, and other symptomatic and supportive medication application of uniform standards, the establishment of a database, all the data related indicators calculated using EXCEL. Chinese Lung Cancer Clinical Guide (2007), \patients with drug reasonable evaluation. Results: a total of 112 people included in the study of patients with malignant, 412 cases of chemotherapy, 861 chemotherapy drugs your doctor and 4609 Chemotherapy drugs and other medical advice symptomatic and supportive treatment. 861 chemotherapy orders properly issued a total of 603 medical advice, medical advice of qualified rate of 70.03%; the 4609 Chemotherapy drugs and other drugs, doctor's orders, a total of 4300 correctly issued by the doctor's advice, medical advice a pass rate of 93.30%. Chemotherapy drugs phenomenon of irrational drug showed dose cisplatin, carboplatin solvent improper selection and administration of the chemotherapy drug concentration, the order of administration, improper use of group interval solution; chemotherapy adjuvant other drugs unreasonable application performance before chemotherapy pretreatment improper, inappropriate route of administration, the ultra-label use; mainly unreasonable combination drug adverse interactions between the joint and there is no evidence to support the effectiveness of the combination therapy. Conclusion: The findings show that the the basic reasonable applications drugs in our hospital Thoracic Surgery cancer patients during chemotherapy, clinicians according to the patient's tumor type, stage, pathological diagnosis, pathophysiology state to develop individualized chemotherapy program, while giving appropriate chemotherapy adjuvant and other symptomatic and supportive treatment. But in some of the drugs on the specific application, there are still some deficiencies, especially chemotherapy drugs such as cisplatin dose in general than standard chemotherapy dose carboplatin of solvent improper selection and pretreatment chemotherapy improper. To promote the rational application of hospital chemotherapy drugs, according to the survey results made the following recommendations: clinical pharmacists should be involved in the whole process of chemotherapy in cancer patients, with a treatment plan with the doctor; clinical pharmacists should pay attention to the administration aspects of the nurse; clinical pharmacist response The patient's course of treatment, care and patients carry medication education.
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