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Objective: To observe the blood Shenduqing retention enema clinical efficacy for the treatment of sepsis and coagulation monitoring indicators (PT, TT, APTT, FBG) to provide new ideas and methods of Chinese and Western medicine treatment of sepsis . Methods: The study was a prospective randomized controlled study , admitted in December 2009 to April 2011 , the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine , ICU sepsis patients met the diagnostic criteria were randomly divided into two groups : the treatment group of 30 patients , The control group of 30 patients . The treatment group received the blood Shenduqing reserved enema and conventional Western medicine treatment control group using the of cleaning enema and Western conventional treatment . All patients included in the study , and seven days for TCM syndrome integral score ; included in the study , 3 days and 7 days , respectively, APACHE Ⅱ and SOFA score detect treatment group , the control group dynamic monitoring indicators of peripheral blood clotting function changes. Results: 1 , the improvement of clinical symptoms : After 7 days of treatment , the two groups of patients with clinical symptoms have improved ( p lt; 0.01 ) , but the treatment group, the clinical symptoms improved more significantly , the difference between groups was significant (P lt ; 0.01). 2 , coagulation monitoring indicators of change : Before treatment, the two groups of patients with TT , PT , APTT were prolonged , FBG reduction groups showed no significant difference ( P gt ; 0.05 ) ; 3,7 days the two groups TT , PT, APTT were shorter ( P lt; 0.01 ) , FBG increased , but the improvement of the control group magnitude less than the treatment group , the difference between groups was significant ( P lt; 0.01 ) . 3, APACHE Ⅱ score , SOFA score : the scores of the two groups of patients before treatment were significantly higher groups showed no significant difference (P gt; 0.05); during treatment , the scores of patients along with the improvement of the disease the downward trend (P lt; 0.01); 3 and 7 days of treatment group scores significantly lower than the control group , the difference between groups was significant sex ( P lt ; 0.01) . Conclusion : Blood Shenduqing retention enema with a significant improvement in clinical symptoms of patients with sepsis and coagulation , and good security .
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