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Objective: To take advantage of the computer image analysis method Polish high-energy ultraviolet and joint clinical efficacy and safety of traditional Chinese medicine anti Bai Ling cream in the treatment of vitiligo. Methods: 62 patients with vitiligo were randomly divided into three groups. Anti-the Bai Ling groups (20 patients with 36 lesions) to anti-Bai Ling cream coated in target lesions at 2 times a day. The high-energy ultraviolet light group (20 patients with 35 lesions) to the medium-wave high-energy ultraviolet light therapy two times a week. Combination group (22 cases, a total of 32 lesions) to the medium-wave high-energy ultraviolet light treatment, two times a week, combined with traditional Chinese anti Bai Ling cream coated target lesions, 2 times a day. Three treatment groups observed treatment lasted for 8 weeks before treatment, after two weeks of treatment, and after four weeks, six weeks and 8 weeks after the observation of the target lesions photographed and depicted, and using computer image analysis system The lesional area to calculate the extent of lesions repigmentation Evaluation observed adverse skin reaction. Results: After 8 weeks of treatment, the total efficiency of the joint group was 88.26%, better than the anti Bai Ling Group 26.04%, and high-energy ultraviolet group 61.54% (P are lt; 0.01); better than the high-energy ultraviolet group the anti Bai Ling group (P lt ; 0.01); treatment for four weeks, six weeks, eight weeks after reducing the rates of the three groups target lesion area, the combined group than the the anti of Bai Ling groups and high-energy ultraviolet groups, the high-energy ultraviolet group is better than the anti-the Bai Ling groups (P lt; 0.01); recovered relatively effective in patients with high-energy ultraviolet radiation cumulative dose combination group was significantly lower than that of the high-energy ultraviolet group (P lt; 0.01); different gender, age, duration, location, MED value, daylight reaction type, sub- under the influence of factors such as type, stage, reduce the rate of target lesion area among the three groups ≥ 40 years of age in the age range of patients with high-energy ultraviolet skin daylight reaction type group and the combined group of target lesions area reduced rate and type III The patients group anti Bai Ling reduce the rate of target lesion area compared with the high-energy ultraviolet group, there was no significant statistical difference; reduce the rate of other factors under three sets of target lesion area compared with a statistically significant difference (P lt; 0.05), reduce the rate of target lesion area of ??the joint group better than anti-Bai Ling group high energy ultraviolet groups; the target lesions area of ??reducing the rate of the high-energy ultraviolet group better than anti-Bai Ling groups; within three treatment groups the area of ??reducing the rate of target lesions factors, foot and part of the joint group of target lesions area reduced rate compared to the other parts of the poor rate of patients with stable area is reduced than in patients with advanced (P lt; 0.05 ). The main side effects of the high-energy ultraviolet treatment including target lesion site might erythema, blisters, dry desquamation, symptoms of itching or tingling, no exit researchers can not tolerate adverse reactions, topical anti-the Bai Ling frost no significant adverse reactions. Conclusion: Polish high-energy ultraviolet light as a treatment for vitiligo new local means of targeted light therapy is the treatment of high-energy, good efficacy, direct role in vitiligo lesions, irradiation near normal skin, fewer adverse reactions, and patient compliance advantages. Bai Ling Chinese medicine anti cream treatment of vitiligo have a certain effect, the medium-wave high-energy ultraviolet joint the anti Bai Ling cream in the treatment of vitiligo alone significantly better than medium-wave high-energy ultraviolet or Chinese anti Bai Ling cream, combination therapy can also reduce the number of times the cumulative dose of UV irradiation to reduce UV irradiation of adverse reactions occur. Combined with computer image analysis system to calculate the loss of its area of ??evaluation of vitiligo, simple and practical, good reliability, to some extent, to avoid the error of the subjective efficacy evaluation, worth vitiligo clinical research to further improve and promote use of the target skin lesions depicted .
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