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Objective: To observe the impact of the different magnetic field strength of the silicon membrane embedded disk ischemic ophthalmopathy , to investigate the magnetic field of the ischemic eye disease treatment mechanism . Methods : 80 rabbits were randomly divided into 5 groups n = 16 , negative control group , 200GS , 400GS , 800GS group , the positive control group . Left eye produced retinal artery ischemia , respectively 200GS 400GS 800GS diskette sclera after the burial , buried silicone chip control group . Give each group of rabbits the beginning and six months, when measuring ERG (ERG) and eye movement current graph (EOG) . Each group of four rabbits were randomly selected week when the line of fundus fluorescein angiography ( Fundus fluorescein angiography , FFA) check line FFA check again in two weeks time , the FFA examination of the month when the last line . Four serological tests after doing time in a month , put to death , do take the ischemic area eye tissue histological examination . Results 200GS, 400GS, 800GS group and positive control group had varying degrees of ischemia improvement , no improvement in the negative control group . Results: The results of animal experiments : Compared with the control group , the of 200GS group , 400GS , 800GS group the ERG waveform significantly change the negative reaction , lower than normal , not sure , normal , especially in the normal the 800GS group waveform . And FFA filling time is significantly shorter . The test results of histology and antioxidant indicators : Compared with the control group , serum SOD , GSH - PX activity increased , MDA content decreased , and the magnetic field is proportional to the relationship ; addition compared with the control , the retinal tissue bipolar cell layer the apoptosis significantly reduce 800GS group is particularly evident . Conclusion: the silicone coated sclera after burial diskette to effectively improve ischemic symptoms of eye disease through its antioxidant effects .
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