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Objective: Through experimental study to verify the effect of using blood detoxification treatment in nephritic syndrome and through clinical case analysis to summary the treatment characteristics, and to initially explore its mechanism. Method: Using review of research methods to collect clinical data, combined with animal studies, and using SPSS17.0 statistical software to analysis such as frequency analysis, rank sum test, X2 test and nonparametric test and draw the statistical conclusions. Result: 1. Experimental Study: After the experiment, the generally condition of survival of rats in control group, model group, Western group and TCM group have no significant differences, but the model group has a higher mortality rate than other groups; TCM group can decrease the blood D-dimmer to improve the coagulation status, and can improve renal pathological state; from the mean and standard deviation of view, there is a certain degree of improvement of hypoproteinemia and hyperlipidemia, but each group has no significant difference. 2. Clinical Research: The children with nephrotic syndrome who had been used the blood detoxification treatment have a history of repeated relapse; main clinical symptoms by frequency are: Urine with more foam, pitting edema, lower extremity edema, usually easy to cold, red lips, red tongue tip or tongue side, (slightly)thick yellow tongue coating, yellow urine, body fat etc; and have a certain regularity of the main laboratory test. The total effective rate of the clinical signs integral assessment was 93.33%, and symptoms before and after treatment were significantly different between in points. Conclusion: Blood detoxification method can effectively alleviate the hypercoagulable state in children with nephrotic syndrome, and improve hypoproteinemia and hyperlipidemia state.
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