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Background / Objective] This paper is divided into three parts. First, we review the clinical characteristics and influencing factors of chronic kidney disease (Chronic kidney disease, CKD), 5. Refers CKD5 of the traditional chronic renal insufficiency (Chronic renal failure, CRF) renal failure period and uremia. Chinese scholars believe that, according to CKD5 of patients with major clinical manifestations and pathological evolution generally attributed to the Chinese medicine \The \With CKD5 of disease progression in patients with associated impact factors including serum creatinine, blood urea nitrogen, residual renal function, proteinuria, hypertension, anemia, blood lipid abnormalities, hyperuricemia, and water and electrolyte metabolism disorders such. Secondly, we summarize the clinical efficacy and mechanism of action of traditional Chinese medicine delay CKD5 renal dysfunction. Domestic Chinese scholars and some scholars believe that the Japanese Kampo, traditional Chinese medicine (Kampo) to participate in the Integrative therapy can effectively delay the CKD5 patients into dialysis treatment time, and can also reduce the complications of dialysis patients. The treatments include oral administration of traditional Chinese medicine, TCM retention enema, traditional Chinese medicine combined with traditional Chinese medicine combined oral retention enema and colon dialysis Combined TCM retention enema. TCM mechanism for delaying CKD5 renal dysfunction mainly refers to the role of the traditional Chinese medicine to improve glomerulosclerosis and renal interstitial fibrosis, for example, by the impact of the glomerular hemodynamic reduce podocyte injury, inhibiting the expression of transforming growth factor-β adjust lipid metabolism disorders to improve glomerulosclerosis; tubular epithelial cell transdifferentiation by reducing macrophage infiltration, suppress, reduce urinary protein toxic to improve renal interstitial fibrosis. Appear for patients with late CKD5 period calcium / phosphorus metabolism imbalances, state of microinflammatory and uremic toxins accumulate, there is a certain improvement in the role of traditional Chinese medicine. Finally, as the focus of this article, we reported CKD5 TCM syndrome characteristics of the analysis of the relationship between the laboratory parameters. The TCM syndromes is to analyze CKD5 patients characteristics, to clarify the relationship between TCM syndrome characteristics of conventional laboratory indicators, waiting for objective research to provide the basis for the CKD TCM. [Method] The traditional epidemiological retrospective survey collected 100 cases CKD5 of patients with TCM syndrome and laboratory indicators related information, and analysis of TCM syndrome and laboratory indicators, including laboratory parameters including serum creatinine (Serum creatinine, Scr), blood urea nitrogen (Blood urea nitrogen, BUN), residual renal function (Residualrenal function, RRF). urine output (Urine volume UV) the hemoglobin (Hemoglobinassay Hb) red blood cell count (Red blood cell count, RBC). serum total cholesterol (Total cholesterol, TC), serum triglycerides (Triglyceride TG), low-density lipoprotein cholesterol (Low density lipoprotein cholesterol, LDL-C). serum high-density lipoprotein cholesterol (High density lipoprotein cholesterol, HDL-C). serum albumin (Serum albumin, Alb). serum uric acid (Serum uric acid, SUA), potassium (Potassium, K), serum sodium (Sodium, Na), calcium (Calcium, CA2), hyperphosphatemia (Phosphorus, P3) and so on. [Results] in non-hemodialysis patients 47 Example CKD5 of TCM symptoms of lassitude waist and knees, dry mouth and throat, sent off teeth shaking, chills, warm, swollen Nan Xiao, poor appetite, abdominal distension, dizziness, ringing in the ears, nausea, vomiting, lip Violet dark \53 Example CKD5 of hemodialysis patients, the main clinical symptoms in anorexia oliguria, aversion to cold, abdominal cold hi hot drinks, they dry oliguria, dry mouth and throat, looking Koushi white or swarthy, dizziness, tinnitus, hair off teeth shake \abnormal. Scr, SUA increased between the two groups were statistically significant (P lt; 0.05), compared with non-spleen deficiency syndrome. [Conclusion] 47 Example CKD5 of non-hemodialysis patients, TCM syndrome characterized Qiyinliangxu; TCM syndrome characterized spleen deficiency in the 53 cases CKD5 period of hemodialysis patients. Whether or not to accept the hemodialysis basic pathogenesis of CKD5 of patients with spleen and kidney deficiency. Laboratory data for CKD5 hemodialysis patients, can be reduced'' RRF, UV \For CKD5 of non-hemodialysis patients, found no relationship between TCM syndrome characteristics of their laboratory indicators.
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