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Objective: The purpose of this project is to the observed blood Shenduqing treatment of sepsis clinical efficacy and PCT levels change , combined with laboratory parameters , and to explore the mechanism of action for the treatment of sepsis , in order to explore more effective prevention and treatment of sepsis approach and provide useful help to further explore the mechanism of action of the medicine prevention and treatment of sepsis and effect link . Methods: In this study, randomized, control method , 60 cases of sepsis patients met the inclusion criteria were randomly divided into control group and treatment group , 30 in each group , the two groups in age, gender, disease duration , illness and other clinical general information was no significant difference between the treatment group Western sepsis Guide regimen and blood Shenduqing , retention enema , the control group using Western sepsis Guide regimen , one week of treatment , clinical symptoms were observed before and after treatment , clinical symptoms and serum calcitonin levels in blood, urine , liver function , renal function and safety indicators of change . Results: After one week of treatment , the two groups of patients with sepsis symptoms have improved ( p lt ; 0.05 ) , and the treatment group symptom improvement is more obvious . Two groups after treatment procalcitonin water reduced by an average difference ( P lt ; 0.05 ) , compared with before treatment , and the treatment group compared with the control group decreased more significantly . Safety evaluation of the clinical trials, no drug-related security exceptions indicators or abnormal emphasis indicators , suggesting that this product has a good safety conclusions: 1. The blood Shenduqing retention enema improve sepsis clinical symptoms and improve the prognosis of patients with sepsis . 2 . The blood Shenduqing reserved soup enema can be reduced in patients with sepsis serum procalcitonin level , inhibiting the inflammatory response .
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