Dissertation > Excellent graduate degree dissertation topics show

Phylogenetic Study of Baculovirus Genome Based on Markov Model

Author: LiXiaoFang
Tutor: HePingAn
School: Zhejiang University of Technology
Course: Basic mathematics
Keywords: Markov model baculovirus phylogenetic tree protein structure and function protein sequence
CLC: Q939.4
Type: Master's thesis
Year: 2011
Downloads: 15
Quote: 1
Read: Download Dissertation

Abstract


In baculovirus, numerous conserved genes have very important biological functions, and they are important roles in virus evolution and classification. Therefore, proteomic analysis of the all baculovirus based on the method of k-string is an interesting work for research of classification of these baculovirus.In the second chapter, according to the Markov Model, we predict the expected frequency of the 4-string for the 30 baculovirus proteome based on the Markov Model. We scan the actual frequency of these 4-string and calculate the relative abundance of a 4-string for each baculovirus proteome. Then, we construct vector based on the relative frequency and the actual frequency of these 4-string, respectively, to character these baculovirus proteome. According to the defining distance between of the vectors, we obtain the similarities of 30 baculovirus, and analyze their evolution and classification. Our conclusion are almost consistent with the biological evolution relationship, And we point out that the conclusion based on the relative frequency of these 4-string is better than the results based on the actual frequency of these 4-string.In the third and fourth chapter, we find out the proteins, which the most actual frequency 4-string or the greatest relative frequency 4-string occurs in these proteins. And, the functions of these proteins are analyzed to illustrate the role of these 4-tring from the five groups of baculovirus. And the phylogenetic tree of 30 baculovirus are constructed according to the distance matrix based on the actual frequency and relative frequency of 4-string.In the fifth chapter, we present a new method for the similarity analysis of biological sequences. Taking the ND5 protein of nine species as an example, we firstly show the effectiveness of our method. Then, applying the method to lef-8 gene in all baculovirus, the phylogenetic tree of 30 baculovirus is obtained, which is almost consistent with the biology taxonomy.

Related Dissertations

  1. Packet Loss Recovering Technology for Speech Transmission over Network,TN912.3
  2. Research on Domain Entity Attribute and Event Extraction Technology,TP391.1
  3. Isolation and Identification of Infectious Bronchitis Virus in Henan and the Full Genome Sequence Analysis of Isolated Strains HN104 and HN091,S852.65
  4. Establishment of Inderect ELISA for Detection of Antibodies Angainst STLV-1 and Preparation of Hybridoma Cell of Monoclonal Antibodies,R373
  5. Expression of VP2 Gene of Infectious Bursal Disease Virus and Preparation of Monoclonal Antibodies Against the Recombinant VP2 Protein,S852.65
  6. Infectious Bursal Disease Virus Particle Vaccine Research and Its Immune Efficacy Evaluation,S858.31
  7. Expression of Conserved Dopaminergic Neurotrophic Factor in sf9 Cells by Using Bac-to-Bac Expression System,R346
  8. Study on Genes Expression and Function of UDP-glucosyltransferases in the Silkworm, Bombyx Mori,S881.2
  9. Analysis of a hAT Family Transposase Gene in Silkwork, Bombyx Mori,Q75
  10. Construction and Bioactivity Measurement of SpltMNPV Recombinant Virus,S476.1
  11. Molecular Cloning and Oxidative Stress Response of a Sigma Class Glutathione S-transferase in Bombus Ignitus,Q963
  12. High-level Expression and Purification of Fusion Protein Polh-N141,Q78
  13. Expression and Analysis of Membrane Protein Gene BmP(echA)-like in Bombyx Mori Fused with Polynedron,Q78
  14. A Clinical Platform for Full-length Antibody Gene Therapy,R450
  15. Research on Routing Optimization Methods and Network Analysis of Urban Road,P208
  16. Amplification and Sequence Analysis of HCV 1b Full-length Genome,R392.1
  17. Construction and Expression of Divalent H-2D~b/IgG2b Molecule,R744.51
  18. The Epidemiology of Torque-teno Canis Virusat One Suburb in Shanghai and Analysis of the Complete Genome,S858.292
  19. Study on N-glycosylational Modification of Human IgG1-Fc Expressed in Insect and Baculovirus System,R346
  20. Study of Transgenic Technology in Processing Tomato Resist Cucumber Mosaic Virus,Q943.2
  21. Morel mycelium -based identification and molecular systematics,S646

CLC: > Biological Sciences > Microbiology > Microbial taxonomy (System microbiology ) > Virus ( viral )
© 2012 www.DissertationTopic.Net  Mobile