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Qianershu for in Vitro Antimicrobial Experiment and Clinical Observation and Correlation of System Evaluation

Author: WuXiaoZheng
Tutor: WangFei
School: Chengdu University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: QianErshu chronic prostatitis moist heat and blood stasis clinical observation in vitro antimicrobial
CLC: R277.5
Type: Master's thesis
Year: 2012
Downloads: 36
Quote: 0
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Objective:The study through preliminary clinical observation of QianErshu’s treatment to chronic prostatitis (moist heat and blood stasis syndrome), elaborate QianErshu’s Efficacy and possible mechanism in the treatment of chronic prostatitis (Damp-heat Syndrome and stasis), at the same time based on its In vitro antibacterial experiment, clearly indicate whither QianErshu has bacteriostatic and bactericidal effect or not to pathogenic bacteria of chronic prostatitis, through its relevance for system evaluation, affirm the validity of Traditional Chinese medicine for clearing heat and removing dampness and removing blood stasis in the treatment of chronic prostatitis.Methods:According to the method of The self-control, clinical observation Select62cases of chronic prostatitis patients (moist heat and blood stasis syndrome),after4week for a course of treatment, observe before and after curative effect of index. All the results use SPSS17.0statistical analysis, P<0.05expressed the difference was statistically significant. In vitro experimental include the bacteriostatic and bactericidal effects of chronic prostatitis pathogenic bacteria, observe the MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration). System evaluation collect the original study of clearing heat, Removing dampness and blood stasis method and analysis the collected original research data by the the Meta.Results:In62cases, of which1case was eliminated and1case was falling, the experimental results were2cases be cured,32cases be powerfully,24cases be effective and2cases be ineffective, the total effective rate was96.7%, markedly effective rate was56.7%, after treatment curative effect of index has improved significantly which Compare with before treatment.(P<0.05). Tests found no serious adverse reactions and side effects. QianErshu in different Concentration aimed at the seven kinds of bacteria has bactriostasis, QianErshu aimed at Escherichia coli has Bactericidal effect.Meta analysis revealed clearing heat and removing dampness and blood stasis in the total efficiency, prostate fluid leukocyte changes and the effect is better than the method of clearing heat and removing dampness and standard treatment of Western medicine, the score of NIH-CPSI meta analysis results of clearing heat and removing dampness and removing blood stasis in treating effect is better than the standard therapy of traditional Chinese and Western medicine.Conclusion:QianErshu can obviously improve the major clinical symptom and pain symptoms of chronic prostatitis (moist heat and blood stasis syndrome) patients, reduce prostate tradition in the number of white blood cells,which is a safe and effective compound preparations to chronic prostatitis (moist heat and blood stasis syndrome) of. QianErshu in different Concentration aimed at the seven kinds of bacteria has bactriostasis, QianErshu aimed at Escherichia coli has Bactericidal effect, consequently can effectively suppress and kill the common pathogenic bacteria of chronic prostatitis. Correlation of system evaluation shows that clearing heat and removing dampness and blood stasistreat chronic prostatitis have very good advantage.

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