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Abstract:Autoimmune diseases often must use immunosuppressant therapy, but because of the adverse reaction of immunosuppressive appear often may limit the clinical application of immunosuppressant. In recent years, with the deepening of the research of Chinese herbal medicine, found that the effect of the Chinese herbal medicine with immunosuppression, such as tripterygium wilfordii preparations and root of herbaceous peony glucoside total. This is the Chinese herbal medicine treatment autoimmune disease shows a good application prospect. Tripterygium wilfordii much glucoside celastraceae is subtropical plants tripterygium wilfordii root peel separated from the two within the broad epoxy ester compounds, the motherland medicine thinks it has for activating blood circulation and eliminating stasis, qingrejiedu, detumescence, insecticidal [the effect such as bleeding in recent years, the study found that more than tripterygium wilfordii glucoside has immune adjustment, anti-inflammatory, antitumor, antisterility and antibacterial effects, and has been widely used to treat rheumatoid arthritis, glomerulonephritis, lupus erythematosus and all kinds of other autoimmune disease and various skin diseases. Root of herbaceous peony glucoside MaoLang families from the total plant in the extraction of the terrace effective components, the motherland medicine thinks it has raise blood, yiqi, check certified, the effect of dredging, modern medicine found that total root of herbaceous peony glucoside to restrain themselves with immune response, and anti-inflammatory, protect liver, improve sleep, against myocardial ischemia, resistance of anxiety and resistance to convulsions, analgesic effects, and not only to rheumatoid arthritis, autoimmune diseases such as systemic lupus erythematosus (sle) are effective exactly, and clinical multiple disciplines to produce the effect of encouraging. Any kind of drugs in the treatment effect of the play at the same time, have varying degrees of the body to bring some adverse reactions, clinical verification tripterygium wilfordii much glucoside adverse reaction of major involvement digestion, cardiovascular, blood and the uropoiesis reproduction, and other systems; Total root of herbaceous peony glucoside to human body adverse reaction of main show is for the digestive system symptoms. Tripterygium wilfordii much glucoside and root of herbaceous peony glucoside as a total of immunosuppression role Chinese herbal preparations, both has the same pharmacological effects and has different characteristics, in order to better grasp the indications and contraindications, this paper tripterygium wilfordii much glucoside and root of herbaceous peony glucoside of pharmacology and total toxicity comparison.
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