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Comparative Study between Diagnosis and Preoperative Staging by3.0T MRI and MSCT in Gastric Cancer

Author: PanHaiFeng
Tutor: WangJiPing
School: Jilin University
Course: Clinical
Keywords: Gastric cancer TNM staging MRI DWI MSCT
CLC: R445.2
Type: Master's thesis
Year: 2013
Downloads: 79
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Abstract


Objective:With the spread and development of3.0T MRI,the staging of gastric carcinomaare improving.By comparison between3.0T MRI and MSCT in gastric carcinomadetection accuracy and display its situation,and combined with the pathologicalresults, in order to investigate the value of magnetic resonance imaging(MRI)andmulti—slice spiral CT(MSCT) in preoperative staging of gastric carcinoma,andprovide enough information for clinical doctors in distinguishing resectionrange,evaluating difficulty of the surgery, making rational operation plan and takingspecific treatment measures during the operation.Methods:All of45patients are treated by surgery, according to the site is divided intofour types,including gastric fundus and cardia carcinoma (GFC and GCC),gastricbody carcinoma (GBC),Gastric antral carcinoma(GAC) and the type of invadingmore than2parts.All these patients were scanned by CT and MRI Plain andenhancement.Staging according to TNM method,comparing with postoperativepathologic finding,and analyzing the correlation between the two results.Amongthem, adenocarcinoma40, mucoid carcinoma3,signet ring cell carcinoma2.According to locations,including GAC21,CBC12,GFC and GCC10,more than2parts invaded2.The pathological staging is based on TNM staging of American JointCommittee on Cancer(AJCC)and2002the International Union againstCancer(IUCC). Pathological staging results after operation,5T1,9T2,20T3,11T4(picture1-6),12N0,22N1,11N2(picture7-8).The3.0MRI’s total accuracy of Tstaging was91.1%, respectively,T1,T2,T3and T4were80%,88.9%,95%,90.9%.While correspondingly, the MSCT’s total accuracy of T staging was75.6%,T1,T2,T3and T4were for were respectively80%,66.7%),95%,81.8%.MRI isbetter Consistency and High correlation with pathology.The differences in the accuracy rate of T staging are statistically significant by these two inspectionsamong45patients(P<0.05).While there is no statistically significant inpre-operation pathological staging of T1among5cases.3.0MRI’s total accuracy ofN staging was60.0%, respectively,N0,N1, andN2were66.7%,59.1%,54.5%,90.9%. While correspondingly, the MSCT’s total accuracy of N staging was80.0%,N0,N1and N2were for were respectively75.0%,81.7%,81.8%.The differences in the accuracy rate of N staging are statisticallysignificant by these two inspections among45patients(P<0.05).While there is nostatistically significant in pre-operation pathological staging of N0-N2(P>0.05).3.0MRI’s total accuracy of M staging was97.8%, respectively,M0,andM2were100%,80.0%. While correspondingly, the MSCT’s total accuracy of M staging was93.3%,M0andM1were for were respectively95.0%,80.0%.The differences in the accuracyrate of M staging are no statistically significant by these two inspections among45patients(P>0.05),and in pre-operation pathological staging of M0-M1(P>0.05).Results:All of45patients are treated by surgery, according to the site is divided intofour types,including gastric fundus and cardia carcinoma (GFC and GCC),gastricbody carcinoma (GBC),Gastric antral carcinoma(GAC) and the type of invadingmore than2parts.All these patients were scanned by CT and MRI Plain andenhancement.Staging according to TNM method,comparing with postoperativepathologic finding,and analyzing the correlation between the two results.Amongthem, adenocarcinoma40, mucoid carcinoma3,signet ring cell carcinoma2.According to locations,including GAC21,CBC12,GFC and GCC10,more than2parts invaded2.The pathological staging is based on TNM staging of American JointCommittee on Cancer(AJCC)and2002the International Union againstCancer(IUCC).Conclusion: By compared with postoperative pathology, Our research shows3.0TMRI andMSCT have very important value in pre-operative staging of gastric cancer.1.In T staging,3.0TMRI is better than MSCT,especially for advanced gastriccancer, MRI can be a preferred method in pre-operational T staging of gastric cancer.2.In N staging,there is non-significant in GC by these two methods--3.0TMRIand MSCT.There is no statistically significant in pre-operation pathological stagingof N0-N2(P>0.05).However,MSCT is better than3.0TMRI in the total accuracyrate.DWI DWI improves the detection of lymph for its functional magnetic resonanceimaging(FMRI),while it needs comprehensive imaging analysis in telling thelymphatic metastasis,which needs more reacher.3.In M staging,there is no statistically significant in the total accuracy rate inGC by3.0TMRI and MSCT.Maybe this is related to small sample sizes.4.For diagnosing and pre-operational staging of gastric carcinoma,we needcombining with the advantages of the two methods of3.0TMRI and MSCT,whichprovide enough and accurate information for clinical doctors in diagnosis andmaking rational operation plan.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Magnetic resonance imaging
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