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The Related Factor Analysis of Anus-retained Operation in Lower Rectal Cancer

Author: MaMing
Tutor: WangHaiJiang
School: Xinjiang Medical University
Course: Oncology
Keywords: Low rectal cancer Anus-retained operation Related factors Multivariateanalysis
CLC: R735.37
Type: Master's thesis
Year: 2012
Downloads: 61
Quote: 0
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Objective: To study the related factors for anus-retained operation in low-rectalcaner through Logistic regression analysis, and to discuss the independent related factorsof anus-retained operation in lower rectal cancer. In order to help doctors to selectreasonable operation method.Methods: Collected330cases patients’ clinical historyunderwent Anus-retained Operation who with rectal tumors within3cm~7cm above theanal verge in the department of Gastrointestinal Surgery in Turmer Hospital of XinjiangMedical University,from Jan1,2006to Dec31,2009.330patients with lower rectalcancer were divided into two groups according to the methods of operations: theabdominoperineal resection (APR) group and the sphincter preserving (SP) group. Theclinical and pathological data between the two groups were evaluated by Chi-squared testand Logistic regression in SPSS17.0for windows. Analyze the influence factor ofanus-retained operation in rectal cancer.Results: Univariate analysis showed that age,gender, ethnicity, circumference of intramural spread, distance of tumor lower marginfrom anal edge, tumor macropathological type,degree of infiltration and degree ofdifferentiation were correlated with anus-retained operation (P<0.05). Multivariateanalysis showed that distance of tumor lower margin from anal edge, degree ofinfiltration were proved to be independent risk factors of anus-retained operation(P<0.05).Conclusion: circumference of intramural spread, distance of tumor lowermargin from anal edge, tumor macropathological type,degree of infiltration and degree ofdifferentiation were Related factors of anus-retained operation, distance of tumor lowermargin from anal edge and degree of infiltration were important influence factors forselecting reasonable operation method. It has great significance to forecast the chance ofanus-retained operation and formulate rational treatment from the research the factor-interrelated of anus-retained operation.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Intestinal neoplasms > Rectal cancer
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