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Improvement of Ethanol Ablation in Cystic Thyroid Nodules That Can Not to Be Aspired and Related Factors Analysis

Author: ChenShaoHua
Tutor: LvGuoRong
School: Fujian Medical
Course: Medical Imaging and Nuclear Medicine
Keywords: Thyroid nodule Ultrasound Ethanol ablation Open-window intervention needleEthanol ablation Interventional ultrasound Related factors
CLC: R736.1
Type: Master's thesis
Year: 2013
Downloads: 2
Quote: 0
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Abstract


Objective To develope a new type of open-window interventional puncture needle and evaluate its value in drainage and sclerotherapy of cystic thyroid nodules that can not to be aspirated.Method Drill two rectangle window with length of5.0mm and width of1.0mm at the end of the PTC needle dry, and develope a new type of open-window interventional needle,then the efficiency of aspiration of open-window intervention needle compared with porous interventional needle and ordinary PTC needle by the test of aspiring pure coupling agent. Efficacy of sclerotherapy of21thyroid cystic nodules that can not to be aspirated by using open-window intervention needle, compared with in fifty thyroid cystic nodules cases can be aspired by ordinary PTC needle, then evaluate its value in drainage and sclerotherapy of cystic thyroid nodules that can not to be aspirated.Results The aspiring efficiency of pure coupling agent of various specifications of the new open-window intervention needle is obviously superior to the PTC trocar needle and porous needle corresponding specification (P<0.05,or P<0.01,or P<0.001), as the inner diameter larger, the coarse needle dry shorter, the pumping efficiency is much more. Ethanol alation efficacy in the treatment of thyroid cystic nodule that can not be aspired with new open-window intervention needle and thyroid cystic nodule can be aspirated with ordinary PTC needle is no significant difference(therapeutic success rate9442%VS93.7%,P>0.05).Conclusion New open-window intervention needle can be used as the best choose needle in ethanol ablation of cystic thyroid nodules that can not to be aspired. Objective To compare the efficacy of ethanol ablation (EA)of cystic and predominantly cystic thyroid nodules, and to evaluate factors affecting efficacy.Method From october2011to today, a total of148thyroid nodules were treated with EA. EA efficacy in treating cystic and predominantly cystic nodules was compared; Suppose volume reduction rate of nodules>50%as standard and factors related to EA efficacy in each type, including sex,age, initial volume, solid component, vascularity and fluid nature, were evaluated.Results Mean nodule volume decreased from16.8±14.0ml to2.4±1.3ml (mean volume reduction,85.8±8.6%) and the therapeutic success rate was89.2%at last follow-up. EA was significantly more effective in cystic than predominantly cystic nodules (95.4%VS76.9%). Independent predictors of EA efficacy for all nodules included initial volume, solid component and vascularity.Conclusion EA is effective in both cystic and predominantly cystic nodules, especially the former. EA is less effective in large or vascular predominantly cystic nodules.

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CLC: > Medicine, health > Oncology > Internal endocrine tumors > Thyroid tumors
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