Dissertation > Excellent graduate degree dissertation topics show

The Effects of Bone Graft in Combination with Splint-like Porcelain-fused-metal(PFM) Bridge on Expression of IL-1β in Gingival Crevicular Fluid

Author: LiZheng
Tutor: HeHuiYu
School: Xinjiang Medical University
Course: Clinical Stomatology
Keywords: periodontopathy bone graft fixed periodontal splint IL-1β GCF
CLC: R783.4
Type: Master's thesis
Year: 2012
Downloads: 12
Quote: 0
Read: Download Dissertation

Abstract


Objective: To compare the restoration method of bone graft in combination withsplint-like PFM bridge treatment and splint-like PFM bridge treatment alone on curingperiodontal disease patients with periodontal bone defects, and giving an estimate for thechanges of IL-1β levels in patients’GCF. Methods:The20patients who`s loosened disalabutment teeth with periodontal bone defects were selected, and divided them into bonegraft group and non-bone graft group. In the bone graft group,10patients’ loosened distalteeth were given bone graft in combination with splint-like PFM bridge treatments. Whilethe other10patients’ loosened distal teeth were treated by splint-like PFM bridge only. Allthe patients were followed up by6to12months, periodontal clinical index(PD、CAL)and content of IL-1β in patients’ GCF were measured, X-ray were taken before surgery,analyzed the changes, meanwhile marked the results. Results:(1)After6month, all thepatients’ IL-1β levels have decreased. Statistical difference was been found in two groupsbetween0/3/6month(P<0.05), comparing with the bone graft group and the non-bonegraft group,the effect of bone graft group was better than another group(P<0.05).(2)ThePD, CAL value (the basic treatment was completed) between bone graft group and thenon-bone graft group had no statistical difference (P>0.05),their periodontal baselinewere comparable. Comparing with PD and CAL from0to6month in bone graftgroup,statistical difference was found (P<0.05),however,the various periodontal indexin non-bone graft group had no statistical difference in the period of0、3、6month (P>0.05).The average bone loss was not found in two groups. Partially bone reconstructionwas found in all the loosened disal teeth in the bone graft group after6months.Conclusion:(1)The bone graft group in combination with splint-like PFM bridgetreatments is better than the other group, the periodontal disease patients with periodontalbone defects can receive better treatment effect on maintaining and promoting periodontalhealth.(2)Comparing the clinical results of the bone graft group and the non-bone graftgroup, bone graft in combination with splint-like PFM bridge is effective and beneficial toperiodontal tissue reconstruction with periodontal bone defects.

Related Dissertations

  1. Inhibition of RAW264.7 Macrophage Inflammatory Cytokines Release by Guggulsterone,R285
  2. Cloning, Expression and Bioactivity Analysis of Goat Interleukin-1β and Interleukin-6,S827
  3. Noble Dendrobium Polysaccharides Attenuate Learning and Memory Deficits Induced by Lipopolysaccharide and Its Mechanisms in Rats,R285.5
  4. PNS treatment of rabbit lung contusion in rats,R285.5
  5. Effects and Mechanism of Tramadol Combined with Electro-Acupuncture on a Rat Model of Neuropathic Pain,R245
  6. Preliminary Study of Protective Effects of GBE on Human Periodontal Ligament Cells,R285.5
  7. Effects of (-)-Epigallocatechin-3-Gallate on Repair of Scalded Skin in Mice,R285.5
  8. The Experimental Study of Cryotheropy to Cure the Acute Damage of Soft Tissue,R686
  9. The Clinical Research of Treatment of Tongluo Shenggu Decttion and Suppressed, Supporting Bone Grafting on the Early-middle Stage Non-traumatic Osteonecrosis of the Femoral Head (NONFH),R687.3
  10. The Comparative Study of Two Deproteinized Methods on Xenogeneic Bone Graft Substitute Material,R687.3
  11. Drilling Decompression of Femoral Head Bone Graft after Huo Gu Injection Articular Injection Treatment of Avascular Necrosis of the Clinical Observation,R687.3
  12. Treatment of Bone Defect with Bone Allograft and Bone Marrow Stem Cell in Rabbit,R687.3
  13. The vertebral pedicle graft combined with pedicle screw fixation of thoracolumbar fractures,R687.3
  14. Heterogeneous experimental study of biological bone screw,R687.3
  15. Protective Effect of Calcitonin on Articular Cartilage and Subchondral Bone of OA Rat Knee Joint,R684.3
  16. The Application of PEEK Cages and Bone Crumbs In-situ in Anterior Cervical Discectomy with Fusion,R687.3
  17. A 5-year Prospective Study of Sinus Floor Elevation,R783.6
  18. Effects and Mechanism of Simvastatin on LPS-induced a-ENaC mRNA in Lung Alveolar Type Ⅱ Epithelial Cells,R965
  19. Effect of Different PFM Materials on the Level of Endotoxin in Gingival Crevicular Fluid,R783
  20. Experimental Study of the Effects of Platelet-rich Fibrin in the Regeneration of Bone Defects,R782
  21. Vascularized tissue engineered bone combined with autogenous bone graft to repair large bone defects in rabbits,R687.3

CLC: > Medicine, health > Oral Sciences > Oral orthotics > Dentition defect and repair of tooth damage
© 2012 www.DissertationTopic.Net  Mobile