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Objective: 1. Assess the Montreal Cognitive Assessment in the Guangzhou area, aged 65 and above communities in the elderly population of reliability and validity, and the demarcation points. Learn Guangzhou urban and rural ≥ 65 years old group with mild cognitive impairment and dementia prevalence. 3. Understanding of the risk factors for mild cognitive impairment. Methods: A stratified random cluster sampling method selected six neighborhood committees in Guangzhou area, two village committees. The Montreal cognitive tests (MoCA), condensed mental state assessment (MMSE), 15 words of immediate memory, delayed recall and delayed recognition, the neuropsychological test check of ≥ 65 years old. Clinical Dementia Rating Scale (CDR) and the full-blown recession Scale (GDS) to assess the degree of cognitive impairment. American spirit obstacles using the Petersen the standard diagnosis of mild cognitive impairment; 4th edition of the Diagnostic and Statistical Manual (DSM-Ⅳ) standard diagnosis of dementia. Montreal Cognitive Assessment retest in 2 to 3 weeks after the extraction has completed the investigation of the elderly 19. Results: (1) the application of the Montreal Cognitive Assessment: the internal consistency of the Chinese version of the Montreal Cognitive Assessment Cronbach's alpha coefficient of 0.814, retest correlation coefficient of r = 0.70 (P = 0.001). The school criterion validity: the MoCA and MMSE pearson correlation coefficient r = 0.860 (P <0.01); Factor analysis extracted four common factors can explain 63.84% of the total variance, and satisfactory factor loadings on each item in the corresponding factor amount (≥ 0.4). The the MoCA Chinese version of the demarcation points were: illiteracy 13/14, the sensitivity and specificity of 68.6% and 74.2%; primary school 18/19, the sensitivity and specificity of 79.6% and 79.7%; Middle School, and more than 22/23 points The sensitivity and specificity of 81.0% and 83.6%, respectively. The prevalence of mild cognitive impairment: should check 2437 2039 people, real investigation, real investigation was 83.7%. Solid check elderly average (75.93 ± 6.60) years old, men and 818 (40.12%), 1221 (59.88%); cities in 1425 (69.89%), 614 in rural areas (30.11%). Detect 476 cases MCI patients, the crude rate of 23.3% and MCI constitute standardized by the Guangzhou Municipal 2000 population age-standardized prevalence was 19.4%; the ② mild cognitive impairment prevalence cities significantly lower than rural ( 21.0% vs. 28.8%, x ~~ 2 = 20.982, P = 0.000) higher in women than in men (24.8% VS 21.1% x to 2 = 6.584, P = 0.010, standardized 21.4% VS16.7%); ③ The The prevalence of mild cognitive impairment in different age difference was significant (x to 2 = 97.285, P = 0.000), and its prevalence increase with age and higher crude prevalence rate ,85-89-year-old age 34.2%, and the standardized 34.3%; the MCI prevalence differences between the patients with different cultural levels have significantly (x to 2 = 113.578, P = 0.000), years of education, the lower the higher the MCI prevalence. Prevalence of dementia: found 201 cases of patients with dementia, the crude rate of 9.9%, constituted by the the Guangzhou 2000 population age standardized prevalence rate of 6.6%; significantly lower than in rural areas (2) Dementia prevalence cities ( ③ The dementia 8.4% VS 13.2%, x ~ 2 = 17.44, P = 0.000); higher in women than in men (11.7% vs. 7.1% x to 2 = 14.61, P = 0.000, standardized 8.2% VS 4.5%); significant prevalence in different age difference (x to 2 = 219.773, P = 0.000); dementia prevalence growth and increased with age; different cultural levels between patients with dementia prevalence difference was significant (x ~~ 2 = 211.69, P = 0.000), higher by years of education, the lower dementia prevalence. Risk factors for mild cognitive impairment: high blood pressure, diabetes, coronary heart disease, cerebrovascular disease, and hyperlipidemia history, only cerebrovascular diseases prevalence of MCI significant impact (x ~~ 2 = 16.243, P = 0.000). After adjusting for age, gender stratification, high blood pressure, heart disease, diabetes, age <75 years of age ≧ 75 years of age and gender groups MCI prevalence rate had no significant effect (P> 0.05); cerebrovascular diseases can increase the elderly male (χ2 = 16.858, P = 0.000), female (χ2 = 5.32, P = 0.034) and <75 years of age (χ 2 = 18.38, P = 0.000) crowd MCI prevalence; ② multiple logistic regression analysis showed that factors, age (OR = 1.062,95% CI = 1.030-1.095), cultural level (OR = 1.778,95% CI = 1.447-2.211), women (OR = 1.797,95% CI = 1.416-2.279), rural (OR = 1.648 , 95% CI = 1.324-2.051), cerebrovascular disease (OR = 1.6, 95% CI = 1.438-1.822), hyperlipidemia (OR = 1.339,95% CI = 1.020-1.758), smoking (OR = 1.265 , 95% CI = 1.007-1.588) is an independent risk factor for MCI illness. Conclusion: (1) Montreal Cognitive Assessment as a screening tool for community elderly with mild cognitive impairment, its sensitivity and high specificity. (2) ① Guangzhou MCI crude prevalence rate of 23.3% of the population age structure in 2000, Guangzhou standardized standardized prevalence was 19.4%; ② sick women than men in rural areas than in urban; ③ mild cognitive impairment prevalence and increased with age, the highest in the 85-89 year-old age group, and years of education were negatively related. (3) ① Guangzhou dementia crude prevalence rate of 9.9%, constituted by the the Guangzhou 2000 population age standardized standardized prevalence rate of 6.6%; ② dementia prevalence rate is higher in women than in men, rural higher than the city; ③ dementia prevalence with age and increased prevalence and years of education were negatively correlated. (4) years old, female, living in rural, low cultural level, cerebrovascular disease, hyperlipidemia is an independent risk factor for MCI.
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