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Rheumatoid arthritis (rheumatoid arthritis, RA) is a cause not yet clear chronic systemic inflammatory disease, chronic, symmetry, multi-synovial arthritis and joint lesions as the main clinical manifestations belongs autoimmune inflammatory diseases . The disease occurs in the small joints of the hands, wrists, feet, and more common in middle-aged women, recurrent, and will eventually lead to joint deformity and loss of joint function as the disease progresses. At home and abroad treatment is mainly symptomatic treatment for complications and treatment to prevent joint changes. Chinese medicine have a more in-depth understanding of the disease based on their clinical performance and features attributable to the motherland valuable medicine \Purpose: treatment of the disease through the use Bushenzhuanggu party the treatment of rheumatoid arthritis (RA), observation medicine clinical efficacy and safety, to explore the advantages of Integrative treatment of rheumatoid arthritis (RA). Methods: This clinical study using randomized controlled trials, will meet the standards of 61 patients were randomly divided into a treatment group, 31 patients in the control group of 30 patients. The treatment group received Bushenzhuanggu party 200ml, orally twice daily, while taking the force mimatsu and methotrexate; control group to give force mimatsu and methotrexate. Both groups 2 months for a course. Record the two groups of patients before and after treatment, RF, ESR, CRP laboratory parameters change. Results: 1. Comparison of clinical efficacy treatment group total effective rate of 87.1%, the control group, the total effective rate of 80.0%. Comparison of clinical efficacy difference was statistically significant (P lt; 0.05), the treatment group than the control group. Joint symptoms, signs integral before and after treatment were compared between the two groups before and after treatment duration of morning stiffness and joint tenderness index, number of swollen joints, VAS integrator, HAQ integral, hands average grip strength than before treatment, after treatment showed significant improvement (P lt ; 0.05, P lt; 0.01). After treatment, the groups were compared, the difference was significant (P lt; 0.05), the treatment group than the control group. Two groups before and after treatment laboratory parameters were compared before and after treatment RF ESR, CRP have different levels of reduction, the treatment group was significantly more improvement, but the statistical analysis, the difference between the two groups was not statistically significant (P gt; 0.05). Comparative control group of adverse reactions in the two groups before and after treatment. Adverse reactions in 6 patients, and the adverse reactions in the treatment group, only 1 case. However, the statistical analysis, the difference between the two groups no statistical significance (P gt; 0.05). Conclusion: described by the Clinical Efficacy the medicine through Invigorant, the Shujin pain can indeed improve the the RA clinical symptoms, to alleviate the suffering of the patient's RA clinical remission rate. At the same time be able to mitigate the adverse drug reaction with NSAIDs and DMARDs. Integrative Medicine has its unique advantages in the treatment of RA and deserve further study in clinical.
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