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Clinical Observation on YiBanTang in the Treatment of Proteinuria of Chronic Glomerulonephritis (Insufficiency of Both Qi and Yin Syndrome with Heat-toxicity)

Author: FengCheng
Tutor: ZhouWenXiang
School: Hubei University of Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: Chronic nephritis Proteinuria Qiyinliangxu folder heat Half of the soup Clinical Observation
CLC: R277.5
Type: Master's thesis
Year: 2011
Downloads: 23
Quote: 0
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Abstract


Chronic glomerulonephritis referred to as chronic glomerulonephritis, is caused by a variety of causes, an autoimmune disease, primary glomerular occurs in young adults, the duration of protraction. Proteinuria is one of the major clinical manifestations, often accompanied by hematuria, urinary tube, edema, hypertension, and some even renal dysfunction. Glomerular and tubular damage may aggravate the long-term lot proteinuria are independent risk factors affect the patient's kidney function and prognosis. Objective: By observing the half soup clinical efficacy of the treatment of chronic nephritis the proteinuria (Qiyinliangxu, folder heat) to provide a basis for clinical medicine, new treatments for to delay chronic nephritis progress. Reference to the \treatment and hospitalization of chronic nephritis Proteinuria (Qiyinliangxu, folder heat) patients, a randomized controlled experimental methods, divided into a treatment group and 35 cases in the control group of 30 patients. Two groups of patients was statistically analyzed in gender, age, and the symptom score and related laboratory tests had no significant difference comparable. 2. Both groups were given the same diet care and symptomatic treatment, the treatment group was given half of the soup, as a control group taking nephritis rehabilitation tablets a day early in the evening three medication and observed for 12 consecutive weeks. Observed two groups of patients before and after treatment, urine protein, urine red blood cell count, and 24-hour urinary protein, hemoglobin, serum albumin, blood urea nitrogen and serum creatinine. Before and after treatment record time, compare the two groups before and after treatment and after treatment between the two groups of the laboratory tests indicators change. 4 were observed TCM Syndrome: lumbar pain, fatigue, dysphoria hot, looking minimalist, sore throat, dry mouth and throat, puffy, red yellow urine all treat the symptoms before and after the change, Statistics Credits Compare syndrome integral change. The results: 1. Clinical efficacy comparison: the treatment group (35 cases), with a total effective rate of 77.1%; 30 cases of the control group, the total effective rate was 66.7%. Ridit statistical analysis, the difference between the two groups was statistically significant (P lt; 0.05), the treatment group than the control group. 2 the two groups the TCM syndromes comparison: The total effective rate of 88.5%, the control group, the total effective rate was 73.3%, by Ridit statistical analysis, the difference between the two groups was statistically significant (P = 0.029 lt; 0.05 ), the treatment group than the control group. Two groups and the symptom score comparison: both groups before and after treatment: the treatment group of symptoms showed significant improvement, control group, the rest of the symptoms were improved in addition to thirsty; between the two groups after treatment: In addition to urine yellow red with the control group showed no significant difference, the remaining disease the differences were statistically significant (P lt; 0.05). Two sets of biochemical markers comparison: both groups before and after treatment: characterization of two groups of urinary protein, urine red blood cell count, 24-hour urinary protein excretion, blood urea nitrogen, serum creatinine, hemoglobin, serum albumin differences were statistically significance (P lt; 0.05 or 0.01); after treatment between the two groups: the treatment group, urine protein, blood urea nitrogen, serum creatinine, and the control group, the difference was not statistically significance (P gt; 0.05), urinary red blood cell count 24-hour urinary protein, hemoglobin and serum albumin comparison with the control group, the difference was statistically significant (P lt; 0.05) 5. safety observation: the treatment process in the treatment group 1 cases of diarrhea, but adjusted drugs after the symptoms disappear, continue medication, the rest had no significant liver and kidney dysfunction, and side effects. Conclusion: 1. Half of the soup has the effect of hot type proteinuria, hematuria alleviate the chronic nephritis Qiyinliangxu folder. Half soup can effectively improve the chronic nephritis Qiyinliangxu folder hot patients with hemoglobin, serum albumin, lower serum creatinine and blood urea nitrogen and improve kidney function. 3 half soup can effectively improve the chronic nephritis Qiyinliangxu folder the hot in patients with lumbar pain, fatigue, edema, dysphoria fever, sore throat, dry mouth and throat, and other symptoms. 4 half soup without obvious liver and kidney dysfunction and other side effects, safe and effective, and worthy of promotion. Literature Review: awareness of chronic nephritis and proteinuria of chronic nephritis, proteinuria of Traditional Chinese Medicine Research Overview \From the understanding of the etiology and pathogenesis of chronic nephritis, proteinuria, diagnosis and treatment, and clinical classification, subtraction with the disease, Chinese medicine and traditional Chinese medicine extracts describes an overview of Chinese medicine treatment of chronic nephritis, proteinuria. Experience has inherited: \spleen and stomach first, retreatment of the permit, final cure \Half soup both Qingrejiedu anti-virus, but also the spleen and water swelling, prescription contains the of chronic nephritis three first principles treatment philosophy.

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