Dissertation > Excellent graduate degree dissertation topics show

Study on the Preparation and Properties of Magnetic Porous Hydroxyapatite Nano-bioceramic

Author: ShenZuoZuo
Tutor: XuXiaoHong
School: Wuhan University of Technology
Course: Materials Science
Keywords: nano-HA Fe3O4 powders magnetic porous bioceramic sol-gel process hydrothermal method structure and properties
CLC: TQ174
Type: Master's thesis
Year: 2010
Downloads: 164
Quote: 1
Read: Download Dissertation

Abstract


Hydroxyapatite (HA) is a most representative bioactive material,which is widely used as bone-repairing material on clinic.The magnetic field can stimulate primitive cells to differentiate into new bone cells,thus accelerates the healing process of bones.Combining the two will not only solve the issue of biocompatibility but also can induce or stimulate the formation of new bone.In this study, Hydroxyapatite (HA) and magnetic material Fe3O4 were synthesized beforehand,and then some pore forming agent and high temperature adhesive were added to prepare magnetic porous HA bioceramic by sintering method.The phase composition and microstructure of the material were characterized by TG-DTA, XRD, SEM and FE-SEM,and the relationship of composition,process structure with properties was researched.HA nano-powders were prepared by sol-gel process and using Ca(NO3)2·4H2O and P2O5 as starting materials.The optimum process was reacting at 30℃with pH of 8,then heated at 600℃.XRD analysis showed that the the size of HA prepared in this study was 40-50nm with a high crystallinity of 95.03%.This HA began to decompose at 650℃while CaO emerged.Microstructure analysis by FE-SEM indicated that the HA particles were rod and columnar, some of the powder agglomerating.FT-IR analysis showed that there were trace CO32- in the crystal lattice of nano-HA,which was favorable for improving its bionic performance.Magnetic material Fe3O4 was prepared by hydrothermal method.The best sample was obtained by reacting at 140℃for 24h with 2mol/L NaOH in the reactant.SEM and XRD analysis showed that the Fe3O4 synthesized in this study was octahedral with an approximate particle size of 1.5～2.5μm and the crystallinity was 87.70%. The saturated magnetization value of the Fe3O4 in this study was 86.93emu/g, the coercive force was 85Oe, safe to hunman body, which was suitable for bone defect healing.Nano-HA and magnetic Fe3O4 were used as main material,some bioglass and amylum were added as high temperature adhesive and pore forming agent to prepare magnetic porous hydroxyapatite nano-bioceramics of four different formula. The testing results of microstructure and properties showed that the optimum bioceramic sample was formula NO.2 fired at 1020℃, in which the content of HA, Fe3O4,amylum and bioglass was 57.69%,7.69%,11.54% and 23.08% respectively.The porosity of the sample was 45.46%, bending strength was 12.33 MPa, the saturated magnetization value was 61.92emu/g and the the coercive force was 103Oe. XRD analysis indicated that the main crystal phases of the bioceramic were Ca10(PO4)6(OH)2(hydroxyapatite)、Fe3O4(ferroferrite) and y-Fe2O3(y-hematite). SEM analysis showed pores of sample were three-dimensional bonded and well distributed. The pore sizes were different, and the diameters of the macropores were 10-30μm while the micropores were only 1～5μm, which was beneficial to the degradability of the material. Fe3O4 well distributed in the HA matrix, which was favorable for the magnetic properties to functionate. Columnar Ca10(PO4)6(OH)2 crystal grains composed the framework while other crystal grains were distributing around them.All the crystal grains were connected by glass phase,in order to make sure the bioceramic has a high bending strength.

Related Dissertations

  1. Study of Tin Alloy Carbon Composite Used for Lithium Ion Battery,TM912.9
  2. Urothermal Synthesis, Structure and Characterization of Functional Coordination Polymers,O631.3
  3. Synthesis and Characterization of Carbonate Intercalated Layered Double Hydroxides and Their Structure Recovery Properties,TQ424.2
  4. Effect of Reinforcing Materials on the Properties of Nitrile Butadiene Rubber,TQ333.7
  5. 1,3 - propanediamine shrink o-vanillin 3d-4f heteronuclear bimetallic complexes synthesis, structure and properties of,O627.3
  6. A Density Functional Theory Study for Wn C0,± （n=1-6） Clusters,O641.1
  7. Syntheses, Structures and Properties of Metal-organic Coordination Polymers Based on Long-Chain Aromaticmulticarboxylate,O631.3
  8. Study on Preparation and Properties of Polyimide/SiO2 Hybrid Films,TB383.2
  9. Synthesis of Novel Ferrite Pigments and Its Application on Magnetic Inks,TQ622.15
  10. Ortho - phenyl ether type phenolic resin synthesis and ammonia-free molding compound,TQ323.1
  11. The Study of Forming Process and Properties of PTT/PET Skin-Core Composite Monofilament with Large Diameter,TQ340.64
  12. Research on Structure and Mechanical Property of Hook and Loop Fastener,TE931.2
  13. Synthesis, Characterization and Catalytic Properties of Vanadium Oxide Nanomaterials,TB383.1
  14. The Research of the Dye-Sensitized Nanocrystalline TiO2 Solar Cells,TM914.4
  15. Rapid solidification microstructure and properties of titanium alloys,TG146.23
  16. Short and efficient process bull spun PET POY molding technology research,TQ340.642
  17. Absorbent sheet synthesis and modification of,TB34
  18. Preparation and Photo Hydrogen Production Properties of Carbon Materials Modified Nanostructured TiO2 Photocatalysts,TN304
  19. LaB_6 optical properties of first-principles calculations and experimental study,O482.3
  20. Tissure Structure and Rheological Properties Changes of Stomolophus Meleagris,TS254.1
  21. Reasearch on Welding Process and Mechanism of 9Ni Steel for Large LNG Storage Tank,TG457.11

CLC: > Industrial Technology > Chemical Industry > Silicate > Ceramic Industry
© 2012 www.DissertationTopic.Net  Mobile