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The Analysis of Neonatal Thyroid Tunction Reducing in Liaocheng Area from2002to2011

Author: FanLi
Tutor: LiJun
School: Shandong University
Course: Public Health
Keywords: Thyroid function to reduce disease Newborn screening disease Prevalence Treatment effect
CLC: R722.1
Type: Master's thesis
Year: 2013
Downloads: 22
Quote: 0
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ObjectiveAnalysis of liaocheng district from2002to2011, neonatal Congenital thyroid function to reduce disease (Congenital hypothyroidism, CH) infection situation, through the investigation and analysis of liaocheng region and seven county from2002to2011, neonatal Congenital thyroid function to reduce disease (Congenital hypothyroidism, CH) infection situation, looking for relevant risk factors, prevention and treatment of CH liaocheng area in the future to provide guidance, for the future of liaocheng city CH provides data for the further study of the data.MethodIn liaocheng area using the method of retrospective investigation and seven county in2002-2011years,608572cases of neonatal disease screening related statements descriptive analysis and case information and statistical inference. Investigation and detection methods:adopting the time-resolved fluorescence immunoassay (TRFIA) in the detection of neonatal serum thyroid Stimulating hormone (thyroid Stimulating hormone, TSH) value, to recall in venous blood TSH children with abnormal value by chemiluminescence method to detect serum T3, T4and TSH concentrations; With serum TSH was higher than normal, T3, FT4below the normal diagnosis of children with CH. The CH children Parents recall questionnaire, descriptive analysis, to find the influence factors of its pathogenesis, treatment effect, and the application of SPSS17.0software for statistical analysis.Results 1.Liaocheng region in2002-2002,608572cases of neonatal screening for CH,315cases of confirmed CH, CH the positive rate of1:1932, compared with the incidence of1/2034have obvious difference.2.145cases145cases male, female, male female ratio is about1to1.2, the male baby girl (P<0.05).3.To compare the incidence of leaching city and counties, Chipping CH incidence is higher than the city, with statistical significance (P<0.05)4.From2002to open Beginning, with the rising number of screening, diagnosis of CH number is rising year by year, has the highest incidence of71.23(100000)/2010, the lowest was36.79(100000)/2005(P<0.05).5.Confirmed Liaocheng region confirmed315cases of children with CH, season of birth statistics, showed that spring, CH prevalence significantly higher than the summer, autumn winter season, but no statistical difference.6.CH with father or mother’s age between24and30children with CH higher incidence,statistically significant (P<0.05)Conclusion1. Liaocheng region CH incidence rates higher than the national.2. Liaocheng region CH incidence increased year by year, the highest incidence rates in2010.3. Liaocheng region and compared seven county CH incidence, Chiping significantly higher than the other counties.4. Liaocheng region CH incidence rates higher than the national.

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CLC: > Medicine, health > Pediatrics > Newborns, premature children disease > Neonatal disease
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