Dissertation > Excellent graduate degree dissertation topics show

Fabrication of a Shape Memory Hydrogel Based on Imidazole-zinc Ion Coordination for Potential Cell-encapsulating Tubular Scaffold Application

Author: NanWenJing
Tutor: LiuWenGuang
School: Tianjin University
Course: Materials Science
Keywords: shape memory hydrogels vinylimidazole zinc ions cell scaffold
CLC: R318.08
Type: Master's thesis
Year: 2012
Downloads: 2
Quote: 0
Read: Download Dissertation

Abstract


A dipole-dipole reinforced copolymer hydrogel was synthesized by one-stepphotopolymerization of vinylimidazole (VI), acrylonitrile (AN) comonomer in thepresence of polyethylene glycol-based crosslinker. The mechanical properties ofPVI-AN gels was tremendously increased only by chelating several mmol/L zinc ions,which was shown to firmly lock the temporary shape of the gel. Extraction of zincions by complexing agent could facilitate the recovery of permanent shape, and thememory behavior was reversible. The PVI-AN hydrogels supported the growth ofL929cells. The cells-seeded flat hydrogel sheet was folded into a temporary tubularscaffold and fixed in culture medium containing5mmol/L zinc ions. After unfoldingthe tube, the exposed L929cells were shown to adhere well on the surface of gel. It isanticipated that this cells-loaded SM hydrogel could be fixed to a desired shape invitro by small amounts of zinc ions for a potential implantable tissue engineeringscaffold.

Related Dissertations

  1. Design, Synthesis and Antibacterial Activity Research on Styrylimidazole Rersistance to Antibiotic Resistant Bacteria Active Compounds,R96
  2. Separation and Enrichment of Heavy Metals and Biological Materials by the Technique of Emulsion Liquid Membrane,TQ028.8
  3. Development of printed circuit boards in acid copper levelers,TQ153.14
  4. Several fluorescent molecular probe design, synthesis and Ion Recognition Properties,O657.3
  5. Studies on Factor IX/X Binding Protein From Agkistrodon Halys Pallas Venom (ahp Ix/x-bp),R91
  6. Thermosensitive microgels for injectable three-dimensional cell scaffolds,R318.08
  7. Application of Atomic Absorption Spectroscopy (AAS) in Analysis of Biological and Aqueous Samples,X832
  8. Study on Migration of Cadmium and Zinc Ions in the Unsaturated Soils in Nanchang Area,X53
  9. Several pharmaceutical molecules with bovine serum albumin interaction,R91
  10. Zinc ion effect against Streptococcus pneumoniae proteomics research,R378
  11. Preliminary Study on the Preparation of Tissue Engineered Urinary Tract Cell-scaffold Composite and Cutivation of it in Vitro,R318.0
  12. Preparation and Study on β-TCP Cell Scaffolds with High Interconnection,R318.08
  13. Research on Manufacture and Modification of Three-Dimensional Cell Scaffold,R318.08
  14. Study on the Separation of Cu(Ⅱ) and Zn(Ⅱ) in Aqueous Solution by Adsorptive Bubble Fractionation,TQ028
  15. Study on Preparation and Modification of Natural Extracellular Matrix,R318.08
  16. Research on Self-buffer Action of Three-Dimensional Cell Scaffold,R318
  17. Comparative Study on Regeneration of Cartilage on Chitosan, Type Ⅱ Collagen, PGA Scaffold in Vitro by Tissue Engineering,R318.0
  18. Zinc ions in the sympathetic trunk and axonal transport of zinc deficiency on studies of effects of sympathetic trunk,R341;R361
  19. Localization and Expression of Zinc Transporters in Mouse Retina,R322.9
  20. PLGA/HA Scaffolds with MSC for Cartilage Tissue Engineering,R687.3
  21. Biodegradable Hydrogel Potentially Used as Injectable Medical Material,R318.08

CLC: > Medicine, health > Basic Medical > Medical science in general > Biomedical Engineering > General issues > Biomaterial
© 2012 www.DissertationTopic.Net  Mobile