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Background: transient ischemic attack (transient ischemic attack, TIA) is the risk of cerebral infarction warning signal, is the most important independent risk factors for ischemic stroke. TIA etiology and pathogenesis explain the doctrine of microemboli hemodynamic changes in doctrine, vasospasm, pressure on the carotid artery and blood components change, micro emboli doctrine is now the focus of research. Some studies suggest that the higher incidence of stroke within 7d of up to 12.8% after one year, up to 21%. Thus rapid identification and prompt treatment of high-risk patients is extremely important, this hierarchical evaluation of TIA patients so as to reduce the proportion of patients with TIA development of stroke, not a waste of medical resources. The prognostic evaluation scale, such as the California scale, ABCD scale, ABCD2 Scale, but there is a lack of evaluation of the relevant ratings. Another study suggests that the pathogenesis also affect the prognosis of the key factors, but not to conduct a study on the relationship between the two. Therefore we need to create a quick and complete evaluation method filter out high-risk patients, resulting in the first time to work out the right treatment, to reduce the risk of stroke after TIA. In this study, the the ABCD2 score joint digital subtraction angiography (digital subtraction angiography, DSA) results to predict the value of TIA recent stroke risk. Objective: To investigate the joint DSA ABCD2 score to predict the value of the stroke risk in the near future after the TIA episodes. PATIENTS AND METHODS: A retrospective of 90 cases of patients with TIA Eastern Department of Neurology, Affiliated Hospital of Qingdao University Medical College hospital, underwent DSA, grouped according to ABCD2 score, according to the DSA results divided into vascular stenosis ≥ 50% group and vascular stenosis lt; 50% group (DSA negative also included in this group). Inclusion and exclusion criteria: The inclusion criteria were (1) the duration of symptoms lt; 24h, and complete remission ② brain CT to rule out bleeding ③ line DSA, (4) cases complete and correct ABCD2 score. The vascular stenosis North America with symptomatic carotid stenosis test standard heart, the degree of stenosis (%) = (1 - at the narrowest diameter / distal stenosis normal arterial diameter) × 100%, calculated automatically by the DSA machine software. Diagnostic criteria for the diagnosis of cerebral infarction by the Conference in accordance with the fourth cerebrovascular disease. All patients underwent head CT, in the course of seven days for the end of the observation time point. Statistical data SPSS11.5 statistical analysis software. Count data group analysis using X2 test, P lt; 0.05 difference statistically significant. Results: ABCD2 score secondary to cerebral infarction. 90 patients with TIA 7d progress to 14% of the 13 cases of cerebral infarction by total number of cases. 90 patients with TIA ABCD2 score ≤ 3 progress to cerebral infarction in 16 cases of cerebral infarction, cerebral infarction was 1.9% ABCD2 score 4-5, the cerebral infarction incidence was 7.2%, ABCD2 score 5-6 points incidence of 12%, ABCD2 score 6-7 points, cerebral infarction was 20%. Low-risk (0-3 points), medium risk (4-5 points) and high risk (6-7 points) group, the proportion of cerebral infarction occurred 7d, respectively (1.9%, 7.2%, 20%), and different stroke risk stratification of cerebral infarction incidence significantly different (P lt; 0.05). Vascular stenosis ≥ 50% group 2d cerebral infarction incidence of 14%, 7d vascular stenosis ≥ 50% group with vascular lt; 50% group was no significant difference in the incidence of cerebral infarction. Incidence of vascular stenosis and stroke after TIA. TIA patients DSA showed 60 cases ICA system, vascular stenosis in 48 patients (80%), and ≥ 50% stenosis in 35 patients (68.3%). Simple intracranial artery stenosis in 27 patients (45%), pure extracranial artery stenosis in 12 patients (20%) .30 cases of VBA system TIA patients DSA showed vascular stenosis, 20 patients (66.7%), and ≥ 50% stenosis of 14 cases (46.7%). Simple intracranial artery stenosis in 4 cases (13.3%), pure extracranial artery stenosis in 14 patients (46.7%). No significant difference in stroke incidence between the two groups after TIA 7d within the vascular stenosis ≥ 50% group 2d cerebral infarction ratio increased. Conclusion: ABCD2 score predict the TIA recently developed effective method for cerebral infarction, a need to expand the number of cases further observation. This study suggests that cerebrovascular check in the importance of the TIA patients, DSA is important to explore the pathogenesis of TIA check.
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